Results 111 to 120 of about 1,504,818 (288)

Twitch force in human Amyotrophic Lateral Sclerosis

Frontiers in Neurology
IntroductionThis study investigated differences in muscle twitch force between slow and fast progressors of amyotrophic lateral sclerosis (ALS) to better understand disease heterogeneity and identify potential biomarkers of disease progression ...
Laura Libonati, Chiara Cambieri, Marco Ceccanti, Federica Moret, Matteo Di Giulio, Eleonora Palma, Maurizio Inghilleri, Maurizio Inghilleri   +7 more
doaj   +1 more source

Intermittent low-intensity contractions cause a dissociation between maximal motor unit firing rates and changes in torque and contractile speed. [PDF]

Exp Physiol
Abstract The purpose was to test: (1) whether the decline in maximal motor unit (MU) firing rate is an invariable response when maximal voluntary contraction (MVC) torque is reduced following a submaximal muscle fatiguing task; and (2) whether fatigue‐induced slowing of contractile speed and firing rate decline are co‐dependent. Ten participants (three
Zero AM, Dudani RA, Fanous J, Rice CL.
europepmc   +2 more sources

Kinematic Features of Voluntary and Involuntary Head Movements in Cervical Dystonia

Movement Disorders, EarlyView.
Abstract Background Cervical dystonia (CD) has a varied motor presentation, combining abnormal postures with complex involuntary head movements. Classification of these motor patterns remains imprecise, relying on descriptive terminology without robust definitions. Objectives To provide a kinematically‐grounded description of the motor phenomenology of
Thomas Hart, Davide Martino, Larissa R. Heideman, Martijn Beudel, Mark J. Edwards, Anna Sadnicka, Francesca Morgante   +6 more
wiley   +1 more source

In vitro and in vivo muscle mass and strength during the first week of critical illness

Intensive Care Medicine Experimental
Background Loss of muscle mass and strength is provoked by critical illness. Our primary aim was to study the development of muscle atrophy and weakness in vitro in isolated myofibers and in vivo muscle mass and in vitro muscle strength during the first ...
Wout J. Claassen, Isabel M. van Ruijven, Marloes van den Berg, Rianne J. Baelde, Alexcia Fortes Monteiro, Rajvi M. N. Balesar, Sylvia W. Hania, Donald L. van der Peet, Peter J. M. Weijs, Coen A. C. Ottenheijm, Sandra N. Stapel   +10 more
doaj   +1 more source

Gut microbiota-mediated betaine regulates skeletal muscle fiber type transition by affecting m6A RNA methylation and Myh7 expression

Gut Microbes
Skeletal muscle fiber composition is essential for maintaining muscle function and overall health. Growing evidence underscores the pivotal role of the gut-muscle axis in mediating the influence of gut microbiota on skeletal muscle development.
Chao Yan, Yilong Yao, Zhaobo Zhang, Fanqinyu Li, Danyang Fan, Wen Liu, Xinhao Fan, Lingna Xu, Yanwen Liu, Shilong Wang, Mengling Hu, Yalan Yang, Zhonglin Tang   +12 more
doaj   +1 more source

Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review

Movement Disorders, EarlyView.
Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska, Maresa Buchholz, Audrey Iskandar, Marcus Grobe‐Einsler, Thomas Klockgether, Jennifer Faber, Bernhard Michalowsky   +6 more
wiley   +1 more source

Garcinol Promotes the Formation of Slow-Twitch Muscle Fibers by Inhibiting p300-Dependent Acetylation of PGC-1α. [PDF]

Int J Mol Sci, 2023
Yao W, Guo B, Jin T, Bao Z, Wang T, Wen S, Huang F.   +6 more
europepmc   +1 more source

Complex coordination of cell plasticity by a PGC-1α-controlled transcriptional network in skeletal muscle [PDF]

, 2015
Skeletal muscle cells exhibit an enormous plastic capacity in order to adapt to external stimuli. Even though our overall understanding of the molecular mechanisms that underlie phenotypic changes in skeletal muscle cells remains poor, several factors ...
Handschin, Christoph, Christoph Handschin, Kupr, Barbara, Barbara eKupr, Christoph eHandschin, Barbara Kupr   +5 more
core   +1 more source

Effect of a virtual walking and therapeutic exercise‐based intervention on gait and balance in people with incomplete spinal cord injury

PM&R, EarlyView.
Abstract Background People with spinal cord injury (SCI) experience sensory and motor impairments that often require exercise‐based treatments. However, these interventions are challenging due to limited active mobility. Novel rehabilitation approaches, such as those targeting the mirror neuron system, could offer additional benefits.
Sara Mollà‐Casanova, Elena Muñoz‐Gómez, Núria Sempere‐Rubio, Noemí Moreno‐Segura, Marta Inglés, Luis‐Millán González, Pilar Serra‐Añó   +6 more
wiley   +1 more source

Muscle fatigue in patients with severe long COVID: A 2‐year follow‐up study

PM&R, EarlyView.
Abstract Background Fatigue is recognized as one of the most persistent and debilitating symptoms of long COVID, affecting both functionality and quality of life. However, its long‐term effects, especially beyond the first year after infection, remain poorly understood.
Isabella da Silva Almeida, Leandro Gomes de Jesus Ferreira, Marco Aurélio Vaz, Rochelle Rocha Costa, Nicolas Babault, Rita de Cássia Marqueti, João Luiz Quagliotti Durigan   +6 more
wiley   +1 more source