Results 81 to 90 of about 127,937 (288)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Fashion Design: fast fashion x slow fashion [PDF]
, 2017 The article, based on research for Doctoral thesis in Design, discusses the complex relationship between the fashion system and sustainability issues.
Schulte, Neide Köhler, Rosa, Lucas da
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Cleaner and Responsible ConsumptionThe fashion industry plays a pivotal role in societal evolution and economic growth, yet it also stands as a significant contributor to environmental degradation.
Aya Abdelmeguid +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Slow fashion communication on social media: Educating consumers through rational content in Indonesia and Malaysia [PDF]
Amid the inadequate communication studies on slow fashion, this study examines slow fashion communication on social media, with a focus on a content analysis of two slow fashion Instagram accounts in Indonesia and Malaysia, namely @setali.indonesia and
Koudelkova, Petra +4 more
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Slow Fashion in Portugal: An Exploratory Approach [PDF]
, 2023 Dissertation presented as the partial requirement for obtaining a Master's degree in Information Management, specialization in Marketing IntelligenceDespite being an increasingly valuable economic activity worldwide, the fashion industry is also one of ...
Saraiva, Mariana Isabel Santos
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Cogent Business & ManagementGrowing environmental concerns have led to much research on the ethical shift in how people shop. Consumer attitudes toward sustainable products have emerged, though consumers prefer them, and actual purchases remain minimal, showing the existence of the
Pappu Sindhuja +4 more
doaj +1 more source