Results 91 to 100 of about 127,937 (288)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
FROM FAST FASHION TO SUSTAINABLE SLOW FASHION
, 2022 The objective of this thesis is to express a need for sustainability within the fast fashion industry, in the form of cultural movement that acts as alternative to the current means of production, consumption, and philosophies.
Millward-Pena, Isabel Agatha
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Slow Fashions: Making Sense of Sustainable Fashion
, 2013 Slow Fashions reframes debates about fashion and sustainability by exploring the production, consumption and representation of fashion against a backdrop of environmental and ethical concerns, underlining the need for a multi-dimensional approach to ...
König, Anna
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, 2023 Som en reaktion mot fast fashion-rörelsen och de oansvariga konsumtionsmönster som den medför har slow fashion uppstått som ett mer hållbart alternativ i modebranschen.
Andersson, Agnes, Forsgren, Louise
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Designing for Fast and Slow Circular Fashion Systems: Exploring Strategies for Multiple and Extended Product Cycles [PDF]
, 2015 : This paper reviews work conducted by practiced-based textile design researchers based at the University of the Arts London (UAL) who were part of the multi-disciplinary, Swedish-based Mistra Future Fashion research consortium between June 2011 – May ...
Earley, Rebecca, Goldsworthy, Kate
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Slow Fashion Brand’s Digital Marketing: What impact does digital marketing´s slow fashion brand have on e-commerce implementation? [PDF]
, 2023 Dissertation presented as the partial requirement for obtaining a Master's degree in Information Management, specialization in Marketing IntelligenceThis project thesis aims to examine the impact of digital marketing on slow fashion brands through the ...
Pereira, Maria de Lancastre Teotónio
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