Results 111 to 120 of about 828,066 (290)

Tapol bulletin no, 161, March/April 2001 [PDF]

open access: yes, 2001
Contents: Deadly conflict in Central Kalimantan -- Human rights defenders slain in cold blood -- All out war in Aceh as US oil company halts operations -- Suharto-style trials back in fashion -- The birth of a new organisation -- PRD takes Suharto to ...

core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Nonlinear normal modes and spectral submanifolds: Existence, uniqueness and use in model reduction

open access: yes, 2016
We propose a unified approach to nonlinear modal analysis in dissipative oscillatory systems. This approach eliminates conflicting definitions, covers both autonomous and time-dependent systems, and provides exact mathematical existence, uniqueness and ...
Haller, George, Ponsioen, Sten
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Fast Fashion, Slow Transition

open access: yes
In the new ultra-fast fashion era, garment production cycles are accelerated to new heights, while the quality of the garments deteriorates. Key characteristics of the industry are its reliance on cheap manufacturing, overconsumption and short-lived garment use.
openaire   +2 more sources

Steady-state probability density function of the phase error for a DPLL with an integrate-and-dump device [PDF]

open access: yes
The steady-state behavior of a particular type of digital phase-locked loop (DPLL) with an integrate-and-dump circuit following the phase detector is characterized in terms of the probability density function (pdf) of the phase error in the loop ...
Mileant, A., Simon, M.
core   +1 more source

Clothing longevity perspectives: exploring consumer expectations, consumption and use [PDF]

open access: yes, 2015
The production, distribution, use and end-of-life phases of the clothing lifecycle all have significant environmental impacts, but complete lifecycle assessment has identified that extending the active life of garments through design, use and re-use is ...
Cooper, T   +4 more
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Sustainable Clothing Buying Behavior of Generations X and Y [PDF]

open access: yesMarketing i Menedžment Innovacij
This contribution addresses the sustainable clothing buying behaviour of Generations X and Y. The aim of the paper is to analyse the main features of sustainable clothing buying behaviour within Generations X and Y and to suggest some marketing ...
doaj   +1 more source

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