Results 1 to 10 of about 1,273,945 (390)

“I have SMA, SMA doesn’t have me”: a qualitative snapshot into the challenges, successes, and quality of life of adolescents and young adults with SMA

Orphanet Journal of Rare Diseases, 2021
Background With the approval of three treatments for spinal muscular atrophy (SMA) and several promising therapies on the horizon, the SMA adolescent and young adult populations are expected to evolve in the coming years.
Allison Mazzella, Mary Curry, Lisa Belter, Rosángel Cruz, Jill Jarecki   +4 more
doaj   +2 more sources

Shape Memory Alloy (SMA) Actuators: The Role of Material, Form, and Scaling Effects

Advances in Materials, 2023
Shape memory alloys (SMAs) are smart materials that are widely used to create intelligent devices because of their high energy density, actuation strain, and biocompatibility characteristics.
Min‐Soo Kim, J. Heo, H. Rodrigue, Hyun-Taek Lee, S. Pané, Min-Woo Han, Sung-hoon Ahn   +6 more
semanticscholar   +1 more source

Gene Therapy for Spinal Muscular Atrophy (SMA): A Review of Current Challenges and Safety Considerations for Onasemnogene Abeparvovec (Zolgensma)

Cureus, 2023
Spinal Muscular Atrophy (SMA) is a genetic disease that causes weakness and wasting in the voluntary muscles of infants and children. SMA has been the leading inherited cause of infant death.
Tolu Ogbonmide, Rajni Rathore, S. Rangrej, Stedrea Hutchinson, Marcia Lewis, Stephenie Ojilere, Victoria Carvalho, Irenaissia Kelly   +7 more
semanticscholar   +1 more source

Impaired prenatal motor axon development necessitates early therapeutic intervention in severe SMA

Science Translational Medicine, 2021
Fetal delays of SMA motor axon radial growth coupled with rapid postnatal degeneration require very early delivery of SMN induction treatments. The sooner, the better Gene therapy approaches hold promise for the treatment of spinal muscular atrophy (SMA).
L. Kong, D. Valdivia, C. Simon, Cera W. Hassinan, N. Delestrée, Daniel M. Ramos, J. Park, Celeste M. Pilato, Xixi Xu, Melissa E. Crowder, Chloe C. Grzyb, Zachary A. King, M. Petrillo, K. Swoboda, Crystal Davis, C. Lutz, Alexander H. Stephan, Xin Zhao, M. Weetall, N. Naryshkin, T. Crawford, G. Mentis, C. Sumner   +22 more
semanticscholar   +1 more source

Implementasi Layanan Informasi menggunakan Media Interaktif berbasis Powerpoint untuk Meningkatkan Pemahaman Program Peminatan Siswa SMA

Pamomong, 2021
Peminatan peserta didik merupakan program kurikuler yang disediakan untuk mengakomodasi pilihan minat, bakat dan/atau kemampuan peserta didik dengan orientasi pendalaman mata pelajaran dan/atau muatan kejuruan.
Choirunisa’ Choirunisa’
doaj   +1 more source

Twitter ve Kamusal Alan Kavramı Üzerine Bir İçerik Analizi: Spinal Musküler Atrofi (SMA) Hastası Çocukların Kampanyalarıyla İlgili Örnek Olay Çalışması

Türkiye İletişim Araştırmaları Dergisi, 2021
Twitter, günümüzde bireylerce ekonomiden siyasete, günlük yaşamdan sanata kadar birçok konununtartışılıp görüş bildirildiği sosyal medya platformlarından biri haline gelmiştir.
Dinçer Adiller, Meltem Güreller
doaj   +1 more source

Hysteretic response and failure behavior of an SMA cable‐based self‐centering brace

Structural Control & Health Monitoring, 2021
This study explores the experimental response and failure behavior of an SMA cable brace. The kernel of the developed SMA brace consists of four SMA cables with a diameter of 8 mm.
F. Shi, Yun Zhou, O. Ozbulut, F. Ren
semanticscholar   +1 more source

PEMAHAMAN GURU KIMIA SEKOLAH MENENGAH ATAS TENTANG PENILAIAN KEMAMPUAN BERPIKIR TINGKAT TINGGI DAN IMPLEMENTASINYA

EDUSAINS, 2020
HIGH SCHOOL CHEMISTRY TEACHERS' UNDERSTANDING OF HIGHER-ORDER THINKING SKILLS AND ITS IMPLEMENTATION Abstract Teachers play an essential role in attempts to develop students' higher-order thinking skills through the implementation of classroom ...
Nurmawati Nurmawati, Elin Driana, Ernawati Ernawati   +2 more
doaj   +1 more source

Awareness screening and referral patterns among pediatricians in the United States related to early clinical features of spinal muscular atrophy (SMA)

BMC Pediatrics, 2021
Background Spinal Muscular Atrophy (SMA), a leading genetic cause of death in infants, is an autosomal recessive neuromuscular disease characterized by progressive muscle weakness and atrophy. While early diagnosis of SMA is critical to modifying disease
Mary Curry, Rosángel Cruz, Lisa Belter, Mary Schroth, Megan Lenz, Jill Jarecki   +5 more
doaj   +1 more source

INNOVATIVE USE OF SHAPE MEMORY ALLOYS AS REINFORCEMENTS FOR CONCRETE BEAM-COLUMN JOINTS: AN OVERVIEW

Mağallaẗ Al-kūfaẗ Al-handasiyyaẗ, 2023
Shape memory alloys have two unique properties of shape memory effect (SME) and superelasticity (SE) that are the ability for large inelastic deformations recovery after heating (SME) and stress removal (SE).
Mahdieh Sabbaghian, Mohammadzaman Kabir
doaj   +1 more source