Results 31 to 40 of about 357,035 (311)
Shape memory alloys (SMA) are used in different areas of engineering and science thanks to their unique properties. They also continue to be an innovative material for the sustainable construction industry.
Krzysztof Kuś, Adam Frączyk
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Nusinsersen is now available in Italy for all SMA types. We describe the experience with intrathecal treatment with nusinersen in 50 patients with SMA at the NEMO Center (NEuroMuscular Omniservice Clinical Center) in Milan, a neuromuscular patient ...
Salmin F +17 more
core +1 more source
This study identified the key chemical components based on an analysis of the seasonal variations of ground level PM2.5 concentrations and its major chemical constituents (sulfate, nitrate, ammonium, organic carbon, and elemental carbon) in the Seoul ...
Changhan Bae +4 more
doaj +1 more source
Pre-mRNA splicing-associated diseases and therapies
Precursor mRNA (pre-mRNA) splicing is an essential step in human gene expression and is carried out by a large macromolecular machine called the spliceosome.
Sierra L. Love +3 more
doaj +1 more source
INNOVATIVE USE OF SHAPE MEMORY ALLOYS AS REINFORCEMENTS FOR CONCRETE BEAM-COLUMN JOINTS: AN OVERVIEW
Shape memory alloys have two unique properties of shape memory effect (SME) and superelasticity (SE) that are the ability for large inelastic deformations recovery after heating (SME) and stress removal (SE).
Mahdieh Sabbaghian, Mohammadzaman Kabir
doaj +1 more source
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Submillimeter Array (SMA) Newsletter February 2013
Submillimeter Array (SMA) Newsletter February 2013 Blundell, Raymond Submillimeter Array Newsletter | Number 15 | July 2013 CONTENTS 1 From the Director SCIENCE HIGHLIGHTS: 2 Hierarchical Fragmentation of the Orion Molecular ...
Blundell, Raymond
core +1 more source

