Results 171 to 180 of about 1,611,169 (342)

3D-Printable Platform for High-Throughput Small-Animal Imaging. [PDF]

J Nucl Med, 2020
Carter LM, Henry KE, Platzman A, Lewis JS.   +3 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

A versatile imaging system for in vivo small animal research

, 2008
In vivo small animal imaging has become an essential technique for molecular biology studies. However, requirements of spatial resolution, sensitivity and image quality are quite challenging for the development of small-animal imaging systems.
Qian, Jianguo
core   +1 more source

Agreement between arterial blood pressures measured non-invasively and invasively in anaesthetised sheep

Acta Veterinaria Scandinavica
Background Both invasive and non-invasive blood pressure measuring methods are used in clinical and experimental work in veterinary medicine and several studies validating these methods are published.
Sanna Kaisa Sainmaa, Magdy Adam Hussein Adam, Daniela C. Casoni, Anna Vilhelmiina Huuskonen, Anna Valldeoriola Cardó, Marja Riitta Raekallio, Anna Kristina Mykkänen   +6 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

The reliability of a ball-tipped probe for detection of breached versus non-breached pedicle drill tracts in the thoracolumbar and lumbar spine of a canine large breed cadaveric model

BMC Veterinary Research
Background Spinal stabilization in dogs is challenging, and improper implant placement can result in significant morbidity. Objectives were to evaluate reliability of a ball-tipped probe for detection of breached versus non-breached pedicle drill tracts ...
Ronan A. Mullins, Cristina Ortega, Jason Bleedorn, Marie Pauline Maurin, Seamus Hoey, Jorge Espinel Ruperez, Karl H. Kraus, Scott J. Hetzel, Julien Guevar   +8 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Ultrasound for Small Animal Imaging v1

protocols.io, 2018
Y. Sauve
semanticscholar   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Editorial: Awake functional imaging of small animals

Frontiers in Neuroscience, 2023
Mehdi Behroozi, Onur Güntürkün, Onur Güntürkün, Annemie Van der Linden, Annemie Van der Linden   +4 more
openaire   +4 more sources