Results 61 to 70 of about 1,611,169 (342)

A Three-Dimensional Registration Method for Microus/Micropet Multimodality Small-Animal Imaging

, 2009
Small-animal models are used extensively in disease research , genomics research, drug development and developmental biology. The development of noninvasive small-animal imaging techniques with adequate spatial resolution and sensitivity is therefore of ...
CHEN, LI-YEN;CHENG, WEN-FANG;LI, PAI-CHI, 陳立言;鄭文芳;李百祺   +1 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Imaging of Hepatocellular Carcinoma by Computed Tomography and Magnetic Resonance Imaging: State of the Art [PDF]

, 2009
Hepatocellular carcinoma (HCC) is a very frequent tumor worldwide. Its incidence is linked to the distribution of liver cirrhosis and viral hepatitis, which are the main risk factors for the development of HCC.
Reiser, Maximilian F., Herrmann, Karin A., Zech, Christoph J.   +2 more
core   +1 more source

Dynamic in vivo imaging of small animal brain using pulsed laser diode-based photoacoustic tomography system.

Journal of Biomedical Optics, 2017
We demonstrate dynamic in vivo imaging using a low-cost portable pulsed laser diode (PLD)-based photoacoustic tomography system. The system takes advantage of an 803-nm PLD having high-repetition rate ∼7000  Hz combined with a fast-scanning single ...
P. K. Upputuri, M. Pramanik
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A high resolution prototype small-animal PET scanner dedicated to mouse brain imaging

Journal of Nuclear Medicine, 2016
We developed a prototype small-animal PET scanner based on depth-encoding detectors using dual-ended readout of small scintillator elements to produce high and uniform spatial resolution suitable for imaging the mouse brain. Methods: The scanner consists
Yongfeng Yang, J. Bec, Jian Zhou, Mengxi Zhang, M. Judenhofer, X. Bai, Kun Di, Yibao Wu, M. Rodríguez, P. Dokhale, K. Shah, R. Farrell, J. Qi, S. Cherry   +13 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Development and performance of the small-animal R-SPECT prototype [PDF]

, 2009
[Poster] 4th European Molecular Imaging Meeting, Barcelona, Spain, May 27 - 30, 2009In vivo molecular imaging of small animals has become an essential technique in biomedical research since the introduction of dedicated PeT and SPeCT scanners.
Lage, Eduardo, Villena, José L., Abella García, Mónica, Desco Menéndez, Manuel, Desco, Manuel, Lage Negro, Eduardo, Tapias, Gustavo, Vaquero López, Juan José, Vidal Migallón, I., Carlos, Álvaro de, Vaquero, Juan José, Abella, Mónica, Sisniega, Alejandro, Vidal-Migallón, I.   +13 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Laboratory implementation of edge illumination X-ray phase-contrast imaging with energy-resolved detectors

, 2015
Edge illumination (EI) X-ray phase-contrast imaging (XPCI) has potential for applications in different fields of research, including materials science, non-destructive industrial testing, small-animal imaging, and medical imaging.
A. Olivo, De Ruvo, L, Endrizzi, M., Kallon, G, SPANDRE, GLORIA, G. Spandre, Vincenzi, A, Kallon, G., A. Brez, Hagen, C. K., Olivo, A, L. De Ruvo, Basta, D, P. C. Diemoz, F. A. Vittoria, Hagen, CK, Olivo, A., C. K. Hagen, Spandre, G, Brez, A., M. Marenzana, Brez, A, DELOGU, PASQUALE, Vittoria, F. A., Marenzana, M., Bellazzini, R, Diemoz, P. C., Vincenzi, A., BELLAZZINI, RONALDO, A. Vincenzi, D. Basta, M. Endrizzi, G. Kallon, R. Bellazzini, Diemoz, PC, Vittoria, FA, Delogu, P, Endrizzi, M, Marenzana, M, De Ruvo, L., Basta, D., P. Delogu   +41 more
core   +1 more source