Results 61 to 70 of about 9,855,827 (301)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Report of the gender dimension in the value chain of small-scale fisheries and aquaculture in Southeast Asia [PDF]

open access: yes, 2022
Gender is an encompassing issue that refers to how we should look at everything in certain ways, especially on the economic, social, political, and cultural features and opportunities concerning men and women, and on the impacts of those aspects on them.

core  

The role of certifications and eco-labels in fisheries: a systematic literature review of their benefits and challenges

open access: yesEnvironmental Sciences Europe
Eco-labels are market tools that provide consumers with relevant information, enabling more informed and sustainable purchasing decisions. As fisheries operate on a high production scale, it is possible to dilute the costs of implementing and maintaining
Marília Tenório Gouveia de Melo   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Seasonal variability shapes resilience of small-scale fisheries in Baja California Sur, Mexico.

open access: yesPLoS ONE, 2017
Small-scale fisheries are an important source of food and livelihoods to coastal communities around the world. Understanding the seasonality of fisheries catch and composition is crucial to fisheries management, particularly in the context of changing ...
Kara E Pellowe, Heather M Leslie
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Initiatives and the Way Forward in the Promotion of Small-scale Fisheries

open access: yes, 2010
SEAFDEC has been supporting countries in the Southeast Asian region in the implementation of several initiatives to promote sustainable small-scale fisheries.

core  

Marine megafauna interactions with small-scale fisheries in the southwestern Indian Ocean: a review of status and challenges for research and management [PDF]

open access: yes, 2017
In developing regions, coastal communities are particularly dependent on small-scale fisheries for food security and income. However, information on the scale and impacts of small-scale fisheries on coastal marine ecosystems are frequently lacking. Large
Fennessy, Sean T.   +28 more
core   +1 more source

Women and Children First: the Gendered and Generational Social-ecology of Smaller-scale Fisheries in Newfoundland and Labrador and Northern Norway

open access: yesEcology and Society, 2013
The resilience of small-scale fisheries in developed and developing countries has been used to provide lessons to conventional managers regarding ways to transition toward a social-ecological approach to understanding and managing fisheries.
Barbara Neis   +2 more
doaj   +1 more source

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