Results 61 to 70 of about 64,222 (310)

Managing small-scale fisheries in Colombia

Maritime Studies, 2016
The small-scale fishermen of Colombia face a wide range of problems and conflicts. While many problems are shared among individuals from both the Atlantic and the Pacific coasts (bi-coastal), others are unique to a subset of the communities, only occur on one of the coasts (uni-coastal) or in an individual locality.
Saavedra-Díaz, Lina M., Pomeroy, Robert, Rosenberg, Andrew A.   +2 more
openaire   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Report of the Regional Workshop Towards a New Era of Support for Small-scale Fisheries in Southeast Asia [PDF]

, 2023
The Regional Workshop on Towards a New Era of Support for Small-scale Fisheries in Southeast Asia was organized on 29‒31 August 2023. The Workshop was aimed at 1) compiling the description/recognition/contribution of SSF in the region (or in each country)
Training Department, Southeast Asian Fisheries Development Center
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Initiatives and the Way Forward in the Promotion of Small-scale Fisheries

, 2010
SEAFDEC has been supporting countries in the Southeast Asian region in the implementation of several initiatives to promote sustainable small-scale fisheries.

core  

Women and Children First: the Gendered and Generational Social-ecology of Smaller-scale Fisheries in Newfoundland and Labrador and Northern Norway

Ecology and Society, 2013
The resilience of small-scale fisheries in developed and developing countries has been used to provide lessons to conventional managers regarding ways to transition toward a social-ecological approach to understanding and managing fisheries.
Barbara Neis, Siri Gerrard, Nicole G. Power   +2 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Report of the International Training Course for Fishery Extension Officers in Extension Methodology and Socio-economics of Small-scale Fisheries

, 1992
The SEAFDEC Training Department has conducted regional training programs for fishery extension officers, with assistance from the Royal Netherlands Government under the Netherlands the Programme for Studies in the Region (SIR/DSO), since 1981.
Southeast Asian Fisheries Development Center, Training Department
core  

Characteristics of the shark fisheries of Fiji [PDF]

, 2015
Limited information is available on artisanal and subsistence shark fisheries across the Pacific. The aim of this study was to investigate Fiji’s inshore fisheries which catch sharks.
Adrian-Kalchhauser, I., Brunnschweiler, J. M., Burkhardt-Holm, P., White, W. T., Glaus, K. B. J.   +4 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source