Results 61 to 70 of about 304,792 (298)

Ecosystem Approach to Small Scale Tropical Marine Fisheries [PDF]

open access: yes, 2013
This is a 4-page brochure about a WorldFish led project. Throughout the world, poor fisheries management contributes to resource degradation, poverty, and food insecurity.
E. Kamanyi   +6 more
core  

Managing small-scale fisheries in Colombia

open access: yesMaritime Studies, 2016
The small-scale fishermen of Colombia face a wide range of problems and conflicts. While many problems are shared among individuals from both the Atlantic and the Pacific coasts (bi-coastal), others are unique to a subset of the communities, only occur on one of the coasts (uni-coastal) or in an individual locality.
Saavedra-Díaz, Lina M.   +2 more
openaire   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

The role of certifications and eco-labels in fisheries: a systematic literature review of their benefits and challenges

open access: yesEnvironmental Sciences Europe
Eco-labels are market tools that provide consumers with relevant information, enabling more informed and sustainable purchasing decisions. As fisheries operate on a high production scale, it is possible to dilute the costs of implementing and maintaining
Marília Tenório Gouveia de Melo   +4 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Contributions of small‐scale and longline fishing to sea turtle mortality in the Solomon Islands

open access: yesConservation Letters
A focus of sea turtle management has been reducing bycatch in commercial fisheries, but sustainable harvest for consumption is also an important objective in many nations. Identifying how much different fisheries contribute to turtle mortality could help
Christopher Brown   +6 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Seasonal variability shapes resilience of small-scale fisheries in Baja California Sur, Mexico.

open access: yesPLoS ONE, 2017
Small-scale fisheries are an important source of food and livelihoods to coastal communities around the world. Understanding the seasonality of fisheries catch and composition is crucial to fisheries management, particularly in the context of changing ...
Kara E Pellowe, Heather M Leslie
doaj   +1 more source

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