Results 61 to 70 of about 559,157 (245)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Hybrid-mode control for grid-connected inverters and characteristics comparison with current-source mode and voltage-source mode

open access: yesInternational Journal of Electrical Power & Energy Systems
The grid-connected inverters (GCIs) controlled by traditional Current-Source Mode (CSM) and Voltage-Source Mode (VSM) face challenges in simultaneously meeting the requirements for small-signal stability, power-response, and grid-support.
Feng Han, Xing Zhang, Ming Li
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Coupling Influence on the dq Impedance Stability Analysis for the Three-Phase Grid-Connected Inverter

open access: yesEnergies, 2019
The dq impedance stability analysis for a grid-connected current-control inverter is based on the impedance ratio matrix. However, the coupled matrix brings difficulties in deriving its eigenvalues for the analysis based on the general Nyquist criterion.
Chuanyue Li   +6 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Small signal stability enhancement of WSCC system using PSO based PSS

open access: yesFranklin Open
A number of synchronous generators are used in parallel in contemporary power systems. Studies are regularly carried out to make sure that the generators will work as intended in the case of any malfunctions or modifications to the system conditions. The
R. Ramya   +3 more
doaj   +1 more source

Small Signal Stability Analysis of Grid Connected Photovoltaic

open access: yesIndonesian Journal of Electrical Engineering and Computer Science, 2017
This paper primarily focuses on the small signal stability analysis of a power system integrated with solar photovoltaics (PV). The test system used in this study is the IEEE 39-bus. The small signal stability of the test system are investigated in terms of eigenvalue analysis, damped frequency, damping ratio and participation factor.
Shalom Lim Zhu Aun   +2 more
openaire   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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