Results 101 to 110 of about 6,718,160 (281)

MicroRNA-126 is a regulator of platelet-supported thrombin generation

Platelets, 2020
Circulating microRNA (miRNA) expression profiles correlate with platelet reactivity. MiR-126 is a promising candidates in this regard. We generated a transgenic zebrafish line with thrombocyte-specific overexpression of miR-126.
Veronika Zapilko, Richard J. Fish, Alix Garcia, Jean-Luc Reny, Sylvie Dunoyer-Geindre, Thomas Lecompte, Marguerite Neerman-Arbez, Pierre Fontana   +7 more
doaj   +1 more source

Tourniquet parent artery occlusion after flow diversion

, 2017
BACKGROUND: The Pipeline Embolization Device (PED) is increasingly used for both on- and off-label purposes for treatment of intracranial aneurysms. The device gradually slows flow of blood into the aneurysm, but the high metal coverage of PED promotes ...
Chen, Stephen, Mokin, Maxim, Kan, Peter, Srinivasan, Visish M., Puri, Ajit S, Duckworth, Edward A. M   +5 more
core   +1 more source

Remote Ischemic Post‐Conditioning Preserves the Neurovascular Unit by Brain‐Derived Gas6 That Drives Monocyte‐Derived Macrophage Reprogramming via Axl and Vimentin after SAH

Advanced Science, EarlyView.
Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu, Zichao Huang, Xi Rong, Xingwei Lei, Fuming Liang, Xiaoguo Li, Jiru Zhou, Yu Wang, Yifan Huang, Shuang Tang, Jianjun Zhong, Jin Yan, Hongji Deng, Chun Zeng, Zongduo Guo   +14 more
wiley   +1 more source

PRIMARY PERCUTANEOUS INTERVENTION (PCI) IN A SAPHENOUS VEIN GRAFT

Pakistan Armed Forces Medical Journal, 2016
Occlusion and degeneration of saphenous vein grafts (SVGs) poses significant problems in patients who have undergone coronary artery bypass graft (CABG) surgery. In the first year post-CABG SVG occlusion rate is approximately 15%.
Shahid Abbas, Qurban Khan
doaj   +2 more sources

An Expertise Transfer Framework For Autonomous Surgical Assistance

Advanced Science, EarlyView.
This study introduces an expertise transfer framework for procedure‐spanning autonomous surgical assistance. By emulating expert logic through hierarchical perception, attention modeling, and knowledge graph‐based decision‐making, the system provides near‐expert surgical view assistance.
Yuan Gao, Guangdi Chu, Wei Jiao, Yuchuan Zhong, Hang Yuan, Chengjun Li, Jinhua Li, Shuxin Wang, Bo Guan, Jianchang Zhao, Lizhi Pan, Haitao Niu, Jianmin Li   +12 more
wiley   +1 more source

Large Vessel Occlusion Identification through Rapid Arterial Occlusion Evaluation

, 2021
Large vessel occlusions account for nearly half of all acute ischemic cerebrovascular accidents and have an increased risk of morbidity and mortality.
Harden, Shirley
core   +1 more source

No evidence that severity of stroke in internal carotid occlusion is related to collateral arteries [PDF]

, 2006
Background/AimThe neurological effects of internal carotid artery (ICA) occlusion vary between patients. The authors investigated whether the severity of symptoms in a large group of patients with ipsilateral or/and contralateral ICA occlusion at ...
?, ?, Wardlaw, J M, Mead, G E, Dennis, M S, Lewis, S C, G E Mead   +5 more
core   +1 more source

Alkylating Agent–Induced FANCL Impairment Damages Pulmonary Arterial, Venous, and Microvascular Endothelial Cells and Predisposes to PAH/PVOD

Advanced Science, EarlyView.
This study establishes a novel cisplatin‐induced rat model of PAH/PVOD and identifies a conserved mechanistic axis—FANCL impairment, DNA damage accumulation, and endothelial dysfunction—triggered by cisplatin or mitomycin C across pulmonary arteries, veins, and microvessels.
Shiyun Liu, Yufei Sun, Xinlei Wu, Haixia Chen, Shaocong Mo, Zichong Li, Yiwei Gong, Xiaoqian Shan, Yuanqi Li, Yaru Guan, Junqi Zhu, Han Yan, Min Du, Feng Wei, Peixin Ou, Ziyi Wang, Chenting Zhang, Lei Xu, Wenju Lu, Jian Wang, Kai Yang   +20 more
wiley   +1 more source

Sustainable Hydrogel‐Forming Microneedle‐Reservoir Patches for Transdermal Delivery of Hydrophilic Macromolecules: Biopolymers, Green Manufacturing and Translation

Advanced Science, EarlyView.
Hydrogel‐forming microneedle (HFMN)‐reservoir patches provide a modular route for controlled transdermal delivery of hydrophilic biomacromolecules. The platform integrates skin‐barrier penetration, sustainable biopolymers, scalable green manufacturing, hydration‐driven transport, model‐cargo validation, and translational quality requirements.
Siddharth Mohanty, Mehmet Onur Aydogdu, Sijia Kang, Xinbo Li, Mohan Edirisinghe   +4 more
wiley   +1 more source

Examining the subcortical infarcts in the era of acute multimodality CT imaging

Frontiers in Neurology, 2016
Background: Lacunar infarcts have been characterized as small subcortical infarcts, resulting from in situ microatheroma or lipohyalinosis in small vessels.
Mindy Tan, Shaloo Singhal, Henry Ma, Henry Ma, Ronil Vikesh Chandra, Jamie Cheong, BENJAMIN B CLISSOLD, BENJAMIN B CLISSOLD, John Ly, John Ly, Velandai Srikanth, Velandai Srikanth, THANH G PHAN   +12 more
doaj   +1 more source