Results 71 to 80 of about 7,015,125 (284)

Monte Carlo simulations of a small-animal PET scanner. Analysis of performances and comparison between camera designs [PDF]

, 2022
The work analyzes the performances (scatter fraction, spatial resolution, sensitivity, image quality) obtained from a 10- detectors small-animal PET, simulated via Geant4 Application for Emission Tomography (GATE), in comparison with other camera ...
Turco, Anna
core  

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Synthesis of [¹⁸F]F-γ-T-3, a Redox-Silent γ-Tocotrienol (γ-T-3) Vitamin E Analogue for Image-Based In Vivo Studies of Vitamin E Biodistribution and Dynamics

Molecules, 2020
Vitamin E, a natural antioxidant, is of interest to scientists, health care pundits and faddists; its nutritional and biomedical attributes may be validated, anecdotal or fantasy.
Peter Roselt, Carleen Cullinane, Wayne Noonan, Hassan Elsaidi, Peter Eu, Leonard I. Wiebe   +5 more
doaj   +1 more source

Spatial resolution of the Inveon small-animal PET scanner for the entire field of view

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2010
In high throughput small-animal positron emission tomography (PET) studies, it can be advantageous to scan more than one animal at the same time. To optimally position these animals in the scanner, both sensitivity and spatial resolution have to be known across the entire field of view (FOV).
Disselhorst, J.A., Boerman, O.C., Oyen, W.J.G., Slump, C.H., Visser, E.P.   +4 more
openaire   +3 more sources

Going beyond the borders : field-of-view extension in MR/PET hybrid imaging [PDF]

, 2012
The recent combination of Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) is of emerging interest in clinical routine. On the one hand, MRI is a widely-used diagnostic tool in medical practice.
Blumhagen, Jan Ole
core   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

Does owning a pet protect older people against loneliness? [PDF]

, 2014
BackgroundPet ownership is thought to make a positive contribution to health, health behaviours and the general well-being of older people. More specifically pet ownership is often proposed as a solution to the problem of loneliness in later life and ...
Victor, Christina, Pikhartova, Jitka, Victor, C, Bowling, Ann, Pikhartova, J, Bowling, A   +5 more
core   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen, Mark Paine, Soohyun Lee, Amir Fazlollahi, Baibin (Ben) Wang, John D. O'Sullivan, Peter J. Nestor   +6 more
wiley   +1 more source

Design study for the ClearPET/XPAD small animal PET/CT scanner

, 2007
International audienceWe present a small animal PET/CT scanner design based on the ClearPET high resolution PET scanner and the XPAD3 hybrid pixel X-ray detector developed at CPPM.
Khodaverdi, M., F. Cassol Brunner, S. Karkar, Loess, J., Cassol Brunner, F., J. Loess, S. Nicol, Morel, C., Nicol, S., M. Khodaverdi, Karkar, S., C. Morel   +11 more
core   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source