Results 1 to 10 of about 3,078 (134)
Neuronal surface P antigen (NSPA) as a novel regulator of energy homeostasis and adipose tissue metabolism [PDF]
Molecular MedicineBackground Regulation of body weight and glucose homeostasis includes the coordinated activity of hypothalamic neurons and adipocytes within a neuroendocrine network whose dysfunctions underlie obesity, insulin resistance, and type 2 diabetes (T2D).
C. Sofía Espinoza +9 more
doaj +2 more sources
Srr2-dependent SOX2 levels govern the chromatin and transcriptional landscape of adult neural stem cell fate decisions in mouse [PDF]
Genome BiologyBackground Stem cell maintenance and lineage commitment in the nervous system require precise regulation of transcription factors, with SOX2 serving as a pivotal regulator.
Sara Cruces-Salguero +8 more
doaj +2 more sources
Galectin-8 drives ERK-dependent mitochondrial fragmentation, perinuclear relocation and mitophagy, with metabolic adaptations for cell proliferation [PDF]
European Journal of Cell BiologyMitochondria adapt to the cell proliferative demands induced by growth factors through dynamic changes in morphology, distribution, and metabolic activity.
Adely de la Peña +10 more
doaj +2 more sources
Aberrations of Genomic Imprinting in Glioblastoma Formation
Frontiers in Oncology, 2021 In human glioblastoma (GBM), the presence of a small population of cells with stem cell characteristics, the glioma stem cells (GSCs), has been described. These cells have GBM potential and are responsible for the origin of the tumors.
Anna Lozano-Ureña +8 more
doaj +1 more source
Scientific Reports, 2021 Brain aging is a natural process characterized by cognitive decline and memory loss. This impairment is related to mitochondrial dysfunction and has recently been linked to the accumulation of abnormal proteins in the hippocampus.
Angie K. Torres +3 more
doaj +1 more source
Stick around: Cell–Cell Adhesion Molecules during Neocortical Development
Cells, 2021 The neocortex is an exquisitely organized structure achieved through complex cellular processes from the generation of neural cells to their integration into cortical circuits after complex migration processes. During this long journey, neural cells need
David de Agustín-Durán +3 more
doaj +1 more source
Glutaminase isoforms expression switches microRNA levels and oxidative status in glioblastoma cells
Journal of Biomedical Science, 2021 Background Glutaminase isoenzymes GLS and GLS2 play apparently opposing roles in cancer: GLS acts as an oncoprotein, while GLS2 (GAB isoform) has context specific tumour suppressive activity. Some microRNAs (miRNAs) have been implicated in progression of
Juan de los Santos-Jiménez +20 more
doaj +1 more source
Pro-Tumoral Functions of Autophagy Receptors in the Modulation of Cancer Progression
Frontiers in Oncology, 2021 Cancer progression involves a variety of pro-tumorigenic biological processes including cell proliferation, migration, invasion, and survival. A cellular pathway implicated in these pro-tumorigenic processes is autophagy, a catabolic route used for ...
Cristóbal Cerda-Troncoso +3 more
doaj +1 more source
Revista Colombiana de Filosofía de la Ciencia, 2017 En la era de la tecnobiología, los saberes de la biología frecuentemente se presentan al público general como una vía segura y eficiente para modificar comportamientos humanos patológicos o indeseables empleando medios tecnológicos.
Nahuel Pallitto
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2023 The conventional early secretory pathway and autophagy are two essential interconnected cellular processes that are crucial for maintaining cellular homeostasis.
Diego Tapia +4 more
doaj +1 more source