Results 41 to 50 of about 3,078 (134)

Rituximab Binding Endows CD20+ Extracellular Vesicles With NK Cell‐Activating Properties in B Cell Lymphoma

Journal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.
B cell lymphoma‐derived EVs are intrinsically neutral or suppressive with respect to NK cell activity (panel 1). In the context of rituximab treatment, NK cytotoxicity is enhanced by antibody‐dependent cell‐mediated cytotoxicity (panel 2). Herein we show that, in addition, rituximab recognition of EV‐associated CD20 generates immune complexes that ...
Adrián V. Otero, Paula Soledad Pérez, Belen Gaete‐Ramírez, Gregorio Cordini, Matías Norte, Enriqueta Martínez, Nicolás Marsol, Cecilia Malusardi, Sofía Rivarola, Ana Cantillo, María Luz Leicaj, Constanza Russo, Juan Quarroz Braghini, Federico Penas, Glenda Ernst, Cecilia Cabral, Silvina Palmer, Manuel Varas‐Godoy, Lourdes Arruvito, Matías Ostrowski   +19 more
wiley   +1 more source

Screening of antioxidant activity, antimicrobial properties, and chemical profiles of 31 plant species against Vibrio and Pseudomonas in the Ecuadorian shrimp industry

Journal of the World Aquaculture Society, Volume 57, Issue 4, August 2026.
Abstract Opportunistic pathogens represent a significant threat to shrimp aquaculture, as they can reduce productivity and cause substantial economic losses. Plant‐derived compounds have been investigated as potential alternatives for controlling bacterial infections associated with shrimp farming.
Arleth Gualle, Lourdes M. Orejuela‐Escobar, Diana Celi, Karla Nolivos‐Rodriguez, Daniel Aguilera‐Pesantes, Doménica Vargas, Diego F. Cisneros‐Heredia, Nelson Miranda‐Moyano, Rebeca Cortez‐Zambrano, Eduardo Tejera, António Machado   +10 more
wiley   +1 more source

Fibronectin is required for proper extracellular matrix organization and cardiac outflow tract elongation in Xenopus laevis

Frontiers in Cell and Developmental Biology
IntroductionCongenital heart defects frequently arise from alterations in cardiac outflow tract (OFT) elongation, a process that depends on the coordinated deployment of second heart field (SHF) progenitor cells and their interactions with the ...
Javiera Jorquera, Isidora Sovino, Catalina Jara-Gonzalez, Ignacio Rosales, Paula G. Slater, Paula G. Slater, Cecilia Arriagada   +6 more
doaj   +1 more source

Polymorphisms in Brucella Carbonic Anhydrase II Mediate CO2 Dependence and Fitness in vivo

Frontiers in Microbiology, 2019
Some Brucella isolates are known to require an increased concentration of CO2 for growth, especially in the case of primary cultures obtained directly from infected animals.
Juan M. García Lobo, Juan M. García Lobo, Yelina Ortiz, Yelina Ortiz, Candela Gonzalez-Riancho, Candela Gonzalez-Riancho, Asunción Seoane, Asunción Seoane, Beatriz Arellano-Reynoso, Félix J. Sangari, Félix J. Sangari   +10 more
doaj   +1 more source

Galectin-3, a rising star in modulating microglia activation under conditions of neurodegeneration

Cell Death and Disease, 2022
The advent of high-throughput single-cell transcriptomic analysis of microglia has revealed different phenotypes that are inherently associated with disease conditions.
Juan García-Revilla, Antonio Boza-Serrano, Ana M. Espinosa-Oliva, Manuel Sarmiento Soto, Tomas Deierborg, Rocío Ruiz, Rocío M. de Pablos, Miguel Angel Burguillos, Jose L. Venero   +8 more
doaj   +1 more source

Steatotic Liver Disease at Primary Biliary Cholangitis Diagnosis: Association With Ursodeoxycholic Acid Response and Outcomes

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Background and Aim Steatotic liver disease (SLD) is becoming increasingly prevalent, leading to a higher frequency of primary biliary cholangitis (PBC) cases coexisting with SLD. However, data on its impact in patients with PBC remain scarce.
María Del Barrio, Margarita Sala, Judith Gómez, Diana Horta, Manuel Hernández‐Guerra, Magdalena Salcedo, Silvia Goñi, Raquel Ríos‐León, Ángela Martínez Herreros, Jesús M. González‐Santiago, Javier Martínez, Nerea C. Quintans, Javier Ampuero, María Dolores Antón, Margarita Fernández‐de la Varga, Desamparados Escudero, Ismael El Hajra, Francisca Cuenca Alarcón, Sara Lorente, Raúl J. Andrade, Mar Riveiro‐Barciela, Inmaculada Castello, Mercè Vergara, Raisa Quiñones, Ana Arencibía Almeida, Sonia Blanco Sampascual, Carles Leal, Montserrat García‐Retortillo, Indhira Pérez‐Medrano, Miguel Fernández‐Bermejo, Rosa M. Morillas, Elena Gómez, Javier Tejedor‐Tejada, Mercè Roget, Sergio Rodríguez‐Tajes, Marta Alonso‐Peña, Ana Álvarez‐Cancelo, María‐Carlota Londoño, Álvaro Díaz‐González   +38 more
wiley   +1 more source

Targeting the immunoproteasome in hypothalamic neurons as a novel therapeutic strategy for high-fat diet-induced obesity and metabolic dysregulation

Journal of Neuroinflammation
Objective Obesity represents a significant global health challenge characterized by chronic low-grade inflammation and metabolic dysregulation. The hypothalamus, a key regulator of energy homeostasis, is particularly susceptible to obesity’s deleterious ...
Nicolás Albornoz, Javiera Álvarez-Indo, Adely de la Peña, Eloisa Arias-Muñoz, Alanis Coca, Fabián Segovia-Miranda, Bredford Kerr, Mauricio Budini, Alfredo Criollo, María A. García-Robles, Eugenia Morselli, Andrea Soza, Patricia V. Burgos   +12 more
doaj   +1 more source

Contrasting Effects of an Atherogenic Diet and High-Protein/Unsaturated Fatty Acids Diet on the Accelerated Aging Mouse Model SAMP8 Phenotype

Neurology International
Background/Objectives: Aging has been extensively studied, with a growing interest in memory impairment by a neurobiological approach. Mitochondrial dysfunction is a hallmark of aging, contributing to the aging phenotype; therefore, mitochondrial ...
Jesús Llanquinao, Claudia Jara, Daniela Cortés-Díaz, Bredford Kerr, Cheril Tapia-Rojas   +4 more
doaj   +1 more source

The Trp73 Mutant Mice: A Ciliopathy Model That Uncouples Ciliogenesis From Planar Cell Polarity

Frontiers in Genetics, 2019
p73 transcription factor belongs to one of the most important gene families in vertebrate biology, the p53-family. Trp73 gene, like the other family members, generates multiple isoforms named TA and DNp73, with different and, sometimes, antagonist ...
Margarita M. Marques, Javier Villoch-Fernandez, Laura Maeso-Alonso, Sandra Fuertes-Alvarez, Maria C. Marin   +4 more
doaj   +1 more source

Disruption of Asparagine Synthetase Is Associated to Increased Biomass in Lotus japonicus

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4471-4483, July 2026.
ABSTRACT Asparagine (Asn) constitutes the major form of nitrogen translocated within Lotus japonicus plants. In this work we use knock‐out (KO) LORE1 mutants‐deficient in the asparagine synthetase gene (LjASN1), which is the most highly expressed ASN gene in plants grown under non‐symbiotic (NS) conditions, but much less expressed under symbiotic (S ...
Sara Rosa‐Téllez, Margarita García‐Calderón, David Barbosa Medeiros, Antonio J. Márquez, Alisdair R. Fernie, Marco Betti   +5 more
wiley   +1 more source