Results 61 to 70 of about 1,984,822 (289)
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
DETERMINING POVERTY MAP USING SMALL AREA ESTIMATION METHOD [PDF]
Poverty is a phenomenon that always occurs in every country especially in the developing country such as Indonesia. Poverty is defined as a condition where someone has not capability to fulfill their basic needs (food and ...
Susanto, Irwan, Yuliasih, Eko
core
Robust small area estimation under spatial non-stationarity [PDF]
Geographically weighted small area methods have been studied in literature for small area estimation. Although these approaches are useful for the estimation of small area means efficiently under strict parametric assumptions, they can be very sensitive ...
Baldermann, Claudia +2 more
core +2 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Semi-Parametric Empirical Best Prediction for small area estimation of unemployment indicators
The Italian National Institute for Statistics regularly provides estimates of unemployment indicators using data from the Labor Force Survey. However, direct estimates of unemployment incidence cannot be released for Local Labor Market Areas.
Alfo', Marco +3 more
core +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Demographic estimation becomes a problem of small area estimation when detailed disaggregation leads to small cell counts. The usual difficulties of small area estimation are compounded when the available data sources contain measurement errors.
Junni L. Zhang, John Bryant
doaj +1 more source
Calibrated Weighting for Small Area Estimation
Calibrated weighting methods for estimation of survey population characteristics are widely used. At the same time, model-based prediction methods for estimation of small area or domain characteristics are becoming increasingly popular.
Chambers, R. L.
core
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source

