Results 51 to 60 of about 5,772,088 (305)

If it sells more, it accomplish less? Brazil between international regulations and the expansion of its defense industry

open access: yesRevista de Estudios Brasileños, 2017
The increase of international attention regarding the theme of small arms has generated several actions that demonstrate this concern. Multilateral and non-governmental organizations, such as the UN and Caritas, record the use of small arms in many of ...
Flavia DE ÁVILA   +1 more
doaj   +1 more source

Personal Armour Testing versus Small Arms Ammunition when the Test Standard Doesn’t Fit [PDF]

open access: yesProblemy Mechatroniki, 2015
Small arms ammunition which may impact personal armour and is deemed to be realistic as a threat by the user, may not always comply with armour test standards.
Philip GOTTS
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Published in Switzerland by the Small Arms Survey [PDF]

open access: yes, 2012
All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, without the prior permission in writing of the Small Arms Survey, or as expressly permitted by law, or under ...
Copy-edited Tania Inowlocki   +6 more
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Infiltration of Small Arms and Light Weapons into Benue Valley and Its Impact on the Conflict Between Pastoralists and Farmers

open access: yesInternational Studies Journal, 2023
One of the challenges confronting nation states is the proliferation of small arms and light weapons. This problem is more pronounce in developing countries where there are porous borders and weak institutions responsible for border security like ...
Paulina Ada Akpa   +2 more
doaj  

Substantive international law limitations and problems [PDF]

open access: yes, 2005
The proliferation of small arms and light weapons (SALW) [about 700 million in circulation] has been causing deplorable security and other concerns of international law. SALW are the primary tools of violations/abuses of humanitarian principles by states,
Zeray Yihdego—Weldegiorgis,
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Weaponomics: the economics of small arms [PDF]

open access: yes, 2006
The small arms market has received considerable attention since the end of the Cold War. Small arms may be viewed as the specific capital of rebel groups yet no statistical analysis of this market for weapons has yet taken place due to the absence of data.
openaire   +2 more sources

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