Results 51 to 60 of about 5,772,088 (305)
The increase of international attention regarding the theme of small arms has generated several actions that demonstrate this concern. Multilateral and non-governmental organizations, such as the UN and Caritas, record the use of small arms in many of ...
Flavia DE ÁVILA +1 more
doaj +1 more source
Personal Armour Testing versus Small Arms Ammunition when the Test Standard Doesn’t Fit [PDF]
Small arms ammunition which may impact personal armour and is deemed to be realistic as a threat by the user, may not always comply with armour test standards.
Philip GOTTS
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Published in Switzerland by the Small Arms Survey [PDF]
All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, without the prior permission in writing of the Small Arms Survey, or as expressly permitted by law, or under ...
Copy-edited Tania Inowlocki +6 more
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
One of the challenges confronting nation states is the proliferation of small arms and light weapons. This problem is more pronounce in developing countries where there are porous borders and weak institutions responsible for border security like ...
Paulina Ada Akpa +2 more
doaj
Substantive international law limitations and problems [PDF]
The proliferation of small arms and light weapons (SALW) [about 700 million in circulation] has been causing deplorable security and other concerns of international law. SALW are the primary tools of violations/abuses of humanitarian principles by states,
Zeray Yihdego—Weldegiorgis,
core
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Weaponomics: the economics of small arms [PDF]
The small arms market has received considerable attention since the end of the Cold War. Small arms may be viewed as the specific capital of rebel groups yet no statistical analysis of this market for weapons has yet taken place due to the absence of data.
openaire +2 more sources

