Results 251 to 260 of about 10,866,941 (342)

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Small-cell carcinoma of the cervix with acute-onset psychotic symptoms associated with clinically diagnosed ectopic ACTH production: a case report. [PDF]

Front Oncol
Ozaki K, Fujino J, Niimi K, Iwata-Endo K, Otsuka N, Kobayashi T, Yoshida K, Mogi K, Yoshihara M, Nagao Y, Tamauchi S, Yokoi A, Yoshikawa N, Kajiyama H.   +13 more
europepmc   +1 more source

Upper Urinary Tract Carcinoma With Primary Small Cell Neuroendocrine Cancer—Case Report and Review of Literature [PDF]

Siddhant Kumar, Sunil Pillai Bhaskara, Krishnakanth AVB, Abhijit Shah, Siddalingeshwara Chandragouda Doddamani, Padmaraj hegde, Arun Chawla   +6 more
openalex   +1 more source

REGγ Suppresses Ferroptosis and Induces Drug Resistance by Degrading WDR6 in Chondrosarcoma

Advanced Science, EarlyView.
Here, we identified REGγ as a susceptibility factor in chondrosarcoma. Our study demonstrates that abnormally activated REGγ‐20S proteasome promotes chondrosarcoma development and progression. Further validation in animal models revealed that blocking REGγ function induced ferroptosis, suppressed malignant progression of chondrosarcoma, and uncovered a
Fanrong Liu, Shihui Shen, Dongxia Li, Peilin Shi, Jiaming Xu, Tongxin Lv, Yingying Du, Jingwei Zhang, Bo Yang, Hansen Chen, Zhuoya Peng, Wenjie Ren, Lu Zhang, Sheng Cheng, Tongjin Yin, Wencai Sheng, Lei Li, Juan Wu, Qingcheng Yang, Shuogui Xu, Wei Zheng   +20 more
wiley   +1 more source

Small cell carcinoma of the bladder: Review of pathogenesis, presentation, and management. [PDF]

Bladder Cancer
Simon NI, Kydd AR, Akbulut D, Takeda D, Del Rivero J, Merino M, Redd B, Lindenberg L, Mena E, Chandran E, Gurram S, Boudjadi S, Niglio S, Sharma P, Thomas A, Apolo AB.   +15 more
europepmc   +1 more source

Diagnostic and management in a rare case of double primary carcinoma: metastatic papillary thyroid cancer coexisting with TTF-1/p40 co-expressing non-small cell lung cancer

Yiding Xu, Rongkui Luo, Hongni Jiang, Lin Shi   +3 more
openalex   +1 more source

NIR‐II Light‐Triggered Electron Flow Initiates Cuproptosis‐Centered Thermoelectric‐Immunotherapy for Breast Cancer

Advanced Science, EarlyView.
A NIR‐II light‐activatable thermoelectric nanoreactor converts surface‐bound Cu2+ into bioactive Cu+ via directed electron flow. This spatiotemporally controlled reduction triggers potent cuproptosis and immunogenic cell death, eradicating primary tumors and, together with aPD‐1 therapy, suppressing metastases while establishing durable immune memory ...
Boyu Yuan, Qin Fan, Shushu Chu, Shining Yang, Yuechao Yang, Chenxi Zhang, Jinqiao Zhang, Xinran Qu, Yiju Wei, Xin Wang, Ziliang Dong   +10 more
wiley   +1 more source

Survival analysis of small cell carcinoma of the esophagus: a 15-year retrospective study from a high-incidence region. [PDF]

J Gastrointest Oncol
Zhang W, Yuan J, Yang B, Wang J, Chen M.
europepmc   +1 more source

Incidental Small Cell Neuroendocrine Carcinoma and High-Grade Dysplasia in an Orthotopic Ileal Neobladder Three Decades Post-cystectomy: A Case Report

Gabriana M. Farah, Gabrielle Yankelevich, Becky Madory, Benjamin V. Stone   +3 more
openalex   +1 more source

PDGFRα+/Integrin α2+ Fibroblasts Orchestrate Tumor Budding in Oral Squamous Cell Carcinoma via Mechano‐Metabolic Symbiosis: E‐Cadherin/Integrin α2β1 Adhesion and Mitochondrial Transfer

Advanced Science, EarlyView.
PDGFA/PDGFRα signaling recruits CAFs to OSCC nests, and CAF‐OSCC contact drives tumor budding invasion. Mechanistically, heterotypic adhesion via E‐cadherin/integrin α2β1 activates YAP signaling in OSCC cells, inducing EMT. Concurrently, CAFs transfer mitochondria through TNTs, supplying ATP to fuel invasion.
Yufang Liu, Jiao Li, Juan Liu, Qi Dong, Haoyang Zhang, Yanjin Wang, Huibing Li, Ye Guan, Lei Cao, Manqing Zhang, Fangning Guo, Xue Liu, Zhen Yang, Mengmeng Lu, Hui Liu, Laiping Zhong, Tong Ji, Tingjiao Liu   +17 more
wiley   +1 more source