Results 241 to 250 of about 10,866,941 (342)

RBM12 Maintains Glioma Stem Cells by Activating Amino Acid‐Dependent mTORC1 Signaling via SLC7A5 mRNA Stabilization

Advanced Science, EarlyView.
This study shows that in glioma stem cells (GSCs), RBM12 recruits ALKBH5 to remove m6A from SLC7A5 transcripts, thereby enhancing mRNA stability, which elevates large neutral amino acid (LNAA) levels and activates mTORC1, promoting GSC proliferation, self‐renewal, and tumor growth.
Hong Lei, Wenlong Luo, Shu Zhou, Lihao Wan, Peng Ling, Zhihua Huang, Zhihua Qian, Chenfei Lu, Mengyue Guo, Zhen Xue, Jun Qin, Ningwei Zhao, Jianghong Man, Wenchao Zhou, Zhiqiang Dong, Shutong Xu, Zhipeng Zhou, Xiuxing Wang, Weiwei Tao   +18 more
wiley   +1 more source

Small cell carcinoma of the ovary, hypercalcemic type: a mini review. [PDF]

Front Oncol
Tripepi M, da Costa AG, Chi DS, Lima J, Casanova J.   +4 more
europepmc   +1 more source

Loss of SMARCA4 leads to Intron Retention and Generation of Tumor-Associated Antigens in Small Cell Carcinoma of the Ovary, Hypercalcemic Type.

David Huntsman, Jessica D. Lang, Ritin Sharma, Marcin Kortylewski, Rebecca F. Halperin, Krystal A. Orlando, Bernard E Weissman, Rayvon Moore, Yemin Wang, Timothy G. Whitsett, Lorna Rodriguez-Rodriguez, Victoria David‐Dirgo, Salvatore Facista, Marice Alcantara, Jeffrey M. Trent, Victoria Zismann, Anthony N. Karnezis, Zoe N. Jensen, William P D Hendricks, Patrick Pirrotte, Rochelle Kofman, D. L. ROSE, Krystine Garcia-Mansfield, Lynda Bennett, Elizabeth A. Raupach, Apurva M. Hegde   +25 more
openalex   +1 more source

Hoarseness Is Not Always Benign; In Some Cases, It Heralds Small-Cell Carcinoma [PDF]

Apoorva R, Amrita Suvarna, Mahesh Santharaya   +2 more
openalex   +1 more source

A Metal‐Phenolic Nanocluster Orchestrates Mito‐Ca2+ Metabolic Autonomy for Tumor Ca2+ Interference Therapy

Advanced Science, EarlyView.
Tumor Ca2+ interference therapy suffers from self‐protective Ca2+ metabolic autoregulation. In this scenario, a versatile metal‐phenolic nanocluster (TCMH) is engineered to modulate mitochondrial calcium uniporter (MCU) ‐mediated mito‐Ca2+ metabolic autonomy.
Ronglong Chen, Jia Huang, Yuepeng Wang, Shucong Yao, Fei Wu, Juan Liu, Chunxue Song, Li Lin, Xijun Lin, Yingjie Deng, Chao Zhang, Zhiquan Huang, Zixian Huang, Lisi Xie   +13 more
wiley   +1 more source

Small cell carcinoma of the ovary, hypercalcemic type complicated by enterocutaneous fistula: a case report. [PDF]

J Med Case Rep
Fatima E, Kayani N, Abdul-Ghafar J, Ud Din N.   +3 more
europepmc   +1 more source

Epstein-Barr virus-positive small cell neuroendocrine carcinoma of the nasopharynx

Shuai Luo, Hailin Peng, Ningchao Fu, Yuchun Tang, Lin Cui, Jinjing Wang, Shaoyong Xu   +6 more
openalex   +1 more source

DHODH Drives Sunitinib Resistance Via a Non‐Enzymatic Mechanism by Inhibiting TRIM28 Ubiquitination and Consequent VEGFA Activation in RCC

Advanced Science, EarlyView.
This non‑enzymatic function of DHODH drives sunitinib resistance by competing with TRIM37 to block TRIM28 ubiquitination, thereby stabilizing TRIM28 and activating VEGFA transcription. Disrupting the DHODH–TRIM28 interaction with lisaftoclax restores drug sensitivity.
Shijie Qian, Shihang Pu, Zhipeng Xu, Yiheng Ding, Ling Jin, Baochao Li, Qi Li, Xiaohai Xi, Zengjun Wang, Jiajun Xing, Aiming Xu   +10 more
wiley   +1 more source

Intrathyroidal thymic carcinoma comprising squamous cell and small cell carcinoma components: A case report. [PDF]

World J Clin Oncol
Shan BW, Yu JH, Ren T.
europepmc   +1 more source

Relationship Between EGFR Mutation Status and Clinicopathological Parameters in Non-Small Cell Lung Carcinomas and Correlation of PD-L1 Expression [PDF]

Sumru Cagaptay, Anil Aysal Agalar, Kübra Canaslan, Duygu Gürel, Buket Timur, Emine Çağnur Ulukuş, Fatma İlknur Ulugün, Volkan Karaçam, İlhan Öztop   +8 more
openalex   +1 more source