Results 241 to 250 of about 11,416,703 (301)

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Patterns of central nervous system disease and molecular landscape in epidermal growth factor receptor exon 20 insertion mutated non-small cell carcinoma. [PDF]

Transl Lung Cancer Res
Reyes A, Mambetsariev I, Fricke J, Young JR, Chen BT, Amini A, Ladbury C, Arias-Romero J, Nguyen D, Pisick E, Doctor V, Tan B, Afkhami M, Kareem W, Li X, Salgia R.   +15 more
europepmc   +1 more source

Long-term remission after multimodal therapy in metastatic small cell carcinoma of the ovary, hypercalcemic type: A case report. [PDF]

Gynecol Oncol Rep
Castanet E, Goldzak G, Paraclet G, Grellety T.   +3 more
europepmc   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

A rare large cell variant of small-cell carcinoma of the ovary, hypercalcemic type in a postmenopausal woman: Case report. [PDF]

Medicine (Baltimore)
Liu S, Che S, Jin C, Deng Y, Zhao D.
europepmc   +1 more source

Primary tracheal small cell carcinoma: A case report and discussion of its surgical and oncological management. [PDF]

JTCVS Tech
Chang S, Cooper C, Lo W.
europepmc   +1 more source

Small cell carcinoma of the ovary hypercalcemic type (SCCOHT): About three case reports. [PDF]

Gynecol Oncol Rep
Benichou J, Varinot J, Bossi-Croci R, Bazot M, Sitbon D, Dahan M, Ferrier C, Dabi Y, Touboul C, Lotz J, Darai E.   +10 more
europepmc   +1 more source

Single-cell transcriptomic analysis reveals epithelial and microenvironmental heterogeneity in small cell carcinoma of the esophagus. [PDF]

Front Immunol
Yin X, Li X, Mi L, Hou J, Yin F.
europepmc   +1 more source

Immunotherapy with and without radiotherapy following the diagnosis of bone metastasis for stage IV non-small cell carcinoma. [PDF]

J Cancer Res Clin Oncol
Beyon J, Collins JE, Welch CA, Kamran A.
europepmc   +1 more source

Clinicopathological features and prognosis of small cell carcinoma of the urinary bladder. [PDF]

Asian J Urol
Tian X, Jia H, Liu Y, Liang Y, Yang S, Liang Z, Ma G, Niu H.   +7 more
europepmc   +1 more source