Results 231 to 240 of about 10,866,941 (342)

Atezolizumab, lurbinectedin, tarlatamab, and FOLFIRNOX in a patient with metastatic small cell carcinoma of the anal canal: A case report and review of the literature [PDF]

Ty Moore, Austin Quick, Wilder Widman, Timothy Schieber, Haoran Li   +4 more
openalex   +1 more source

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source

A case report of small-cell carcinoma of the prostate with ectopic adrenocorticotropic-hormone (ACTH) syndrome and hypokalemia. [PDF]

AME Case Rep
Cao XY, Deng HB, Jiang PB.
europepmc   +1 more source

Small cell carcinoma arising in a defunctionalized bladder after urinary diversion for a benign condition: A case report and literature review

Taketoshi Nara, Hiromi Sato, Mizuki Kobayashi, Ryohei Yamamoto, Mitsuru Saito, Shintaro Narita   +5 more
openalex   +1 more source

Association of c-Myc and Immune Cell Infiltration in Small Cell Lung Carcinoma [PDF]

Peiyan Zhao, Hui Li, Xinyue Wang, Na Di, Yan Liu, Lin Tian, Rui Zhong, Changlin Liang, Haifeng Liu   +8 more
openalex   +1 more source

Single‐Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti‐PD‐1 Resistance in Colorectal Cancer

Advanced Science, EarlyView.
Single‐cell RNA editing analysis identifies ADAR1 as a regulator of dysfunctional T cell states in colorectal cancer. Elevated ADAR1 activity promotes T cell exhaustion and impairs antitumor immunity partly through TGF‐β‐SMAD signaling, contributing to anti‐PD‐1 resistance and highlighting T cell ADAR1 as a potential therapeutic target and biomarker ...
Da Kang, Song‐Zuo Xie, Yong‐Zhou Luo, Xin‐Pei Deng, Xi‐Rong Tan, Ze‐Geng Chen, Ling‐Xing Zeng, Gong Chen, Pei‐Rong Ding, Zhi‐Zhong Pan, Rong‐Xin Zhang   +10 more
wiley   +1 more source

Pregnancy-Associated Small Cell Carcinoma of the Ovary, Hypercalcaemic Type Initially Misdiagnosed as Granulosa Cell Tumour: Diagnostic Pitfalls, Treatment Challenges, and Molecular Confirmation by Next-Generation Sequencing. [PDF]

Cancer Rep (Hoboken)
Kumar M, Kakoti L, Barmon D, Baruah U, Begum D, Roy PS, Bassetty KC, Mittal D, Seth B.   +8 more
europepmc   +1 more source

Synchronous primary small cell and squamous cell lung carcinoma with hepatic metastasis from the small cell lung carcinoma: A case report

Meng He, Mingsheng Ma
openalex   +1 more source

A Chemically Defined Four‐Component Self‐Adjuvanting Tn Vaccine Activating Mincle, FcγR, and CD206 for Enhanced Antitumor Immunity

Advanced Science, EarlyView.
A fully synthetic four‐component vaccine has been developed combining Tn antigen, vizantin (Mincle agonist), rhamnose (antibody recruitment), and mannose (CD206 targeting). By synergistically activating Mincle, FcγR, and CD206 pathways, it elicits strong IgG switching and cytotoxic T‐cells, significantly inhibiting tumors in mice.
Wenbo Ming, Renyu Zhang, Xiaohui Li, Guiqi Li, Yu Niu, Deying Yang, Xiang Luo, Jun Liao, Zhongqiu Liu, Guochao Liao   +9 more
wiley   +1 more source

Treatment strategies for small cell carcinoma of the esophagus: comparative analysis of multimodal regimens in two independent real-world cohorts. [PDF]

Oncologist
Yin X, Li X, Mi L, Hou J, Yin F.
europepmc   +1 more source