Results 1 to 10 of about 690,796 (163)
Ca-A Cancer Journal for Clinicians, 1993 Small cell lung cancer is a unique form of lung cancer characterized by rapid growth, dissemination at diagnosis, and responsiveness to both radiotherapy and chemotherapy. It accounts for about one quarter of all lung cancers and, left untreated, results in the shortest survival of any pulmonary neoplasm, with a median survival of two to four months ...
J A Hinson, M C Perry, Michael C Perry
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JAMAImportanceSmall cell lung cancer (SCLC) is a high-grade neuroendocrine carcinoma with an incidence of 4.7 cases per 100 000 individuals in 2021 in the US and a 5-year overall survival of 12% to 30%.ObservationsCigarette smoking is the primary risk factor for development of SCLC, as 95% of patients diagnosed with SCLC have a history of tobacco use ...
Pincott J, Kanchustambham V.
europepmc +3 more sources
Current Problems in Cancer, 1989 Lung cancer is the most common cause of cancer death in the United States, with approximately 135,000 men and women dying each year. While much has been learned about the etiologic risk factors, less progress has been made in therapy. Five-year survival rates remain at less than 10%.
G E, Goodman, R B, Livingston
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Nature Reviews Disease Primers, 2021 Small-cell lung cancer (SCLC) represents about 15% of all lung cancers and is marked by an exceptionally high proliferative rate, strong predilection for early metastasis and poor prognosis. SCLC is strongly associated with exposure to tobacco carcinogens.
Charles M. Rudin +3 more
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Chinese Journal of Lung Cancer, 2023 With the development of precision diagnosis and treatment for non-small cell lung cancer (NSCLC), the epidermal growth factor receptor (EGFR) exon 20 insertion (ex20ins) mutations, as a rare subset of EGFR mutaions, have gradually attracted attention ...
Chinese Society of Clinical Oncology (CSCO) Non-small Cell Lung Cancer Committee
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Journal of the National Comprehensive Cancer Network, 2011 The incidence and mortality of small-cell lung cancer worldwide make this disease a notable health-care issue. Diagnosis relies on histology, with the use of immunohistochemical studies to confirm difficult cases. Typical patients are men older than 70 years who are current or past heavy smokers and who have pulmonary and cardiovascular comorbidities ...
Gregory P, Kalemkerian +21 more
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Journal of the National Comprehensive Cancer Network, 2013 Neuroendocrine tumors account for approximately 20% of lung cancers; most (≈15%) are small cell lung cancer (SCLC). These NCCN Clinical Practice Guidelines in Oncology for SCLC focus on extensive-stage SCLC because it occurs more frequently than limited-stage disease. SCLC is highly sensitive to initial therapy; however, most patients eventually die of
Gregory P, Kalemkerian +25 more
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Expert Consensus on Prevention and Treatment of COVID-19 Infection in Patients with Lung Cancer
Chinese Journal of Lung Cancer, 2023 Corona virus disease 2019 (COVID-19) infection has become a major public health issue affecting human health. The main goal of epidemic prevention and control at the current stage in China is to “protect people’s health and prevent severe cases ...
Non-small Cell Lung Cancer Expert Committee of Chinese Society of Clinical Oncology +1 more
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Annals of Oncology, 2006 Small cell lung cancer accounts for 13-15% of all lung cancer worldwide. There has been a decrease in the number of cases, with no clear explanation, except probably to changing in smoking habits in the last two decades. In the early eighties, it became clear that SCLC was an extremely sensitive tumor as to radiation as to chemotheraputic agents.
Rosti G +5 more
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Surgery in Small-Cell Lung Cancer [PDF]
Cancers, 2021 Small-cell lung cancer (SCLC) is one of the most aggressive tumors, with a rapid growth and early metastases. Approximately 5% of SCLC patients present with early-stage disease (T1,2 N0M0): these patients have a better prognosis, with a 5-year survival up to 50%.
Nicola Martucci +11 more
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