Results 21 to 30 of about 776,387 (309)

MicroRNA-24 in Cancer: A Double Side Medal With Opposite Properties

Frontiers in Oncology, 2020
MicroRNA-24 (miR-24) has been widely studied in a variety of human cancers, which plays different roles in specific type of cancers. In the present review, we summarized the recent surveys regarding the role of miR-24 in different human cancers.
Sumei Wang, Sumei Wang, Sumei Wang, Nayan Liu, Nayan Liu, Nayan Liu, Nayan Liu, Qing Tang, Qing Tang, Qing Tang, Honghao Sheng, Honghao Sheng, Honghao Sheng, Shunqin Long, Shunqin Long, Shunqin Long, Wanyin Wu, Wanyin Wu, Wanyin Wu   +18 more
doaj   +1 more source

Oral vinorelbine and cisplatin with concomitant radiotherapy in stage III non-small cell lung cancer (NSCLC): A feasibility study [PDF]

, 2006
Background: Concurrent chemoradiotherapy has improved survival in inoperable stage III non-small cell lung cancer (NSCLC). This phase I trial was performed in order to establish a dose recommendation for oral vinorelbine in combination with cisplatin and
Schmidt, Michael, Aubert, Delphine, Flentje, Michael, Semrau, Sabine, Fietkau, Rainer, Fittipaldo, Alberto, Huber, Rudolf M., Kleine, Philip, Beckmann, Gabriele   +8 more
core   +1 more source

Lurbinectedin in small cell lung cancer

Frontiers in Oncology, 2022
Few treatment options are available for patients with small cell lung cancer (SCLC) in progression after a first-line therapy. A novel therapeutic approach is represented by lurbinectedin, a synthetic derivative of trabectedin that works by inhibiting oncogenic transcription and promoting apoptosis in tumor cells.
Anna Manzo, Vincenzo Sforza, Guido Carillio, Giuliano Palumbo, Agnese Montanino, Claudia Sandomenico, Raffaele Costanzo, Giovanna Esposito, Francesca Laudato, Edoardo Mercadante, Carmine La Manna, Paolo Muto, Giuseppe Totaro, Rossella De Cecio, Carmine Picone, Maria Carmela Piccirillo, Giacomo Pascarella, Nicola Normanno, Nicola Normanno, Alessandro Morabito   +19 more
openaire   +3 more sources

Development of taxane resistance in a panel of human lung cancer cell lines [PDF]

, 2008
Using a selection process designed to reflect clinically relevant conditions, a panel of taxane-selected variants were developed to study further the mechanisms of resistance in lung cancer.
Keenan, Joanne, Breen, Laura, Murphy, Lisa, Clynes, Martin   +3 more
core   +1 more source

Prognostic significance of folate metabolism polymorphisms for lung cancer. [PDF]

, 2007
Functional nonsynonymous single-nucleotide polymorphisms (nsSNPs) of folate metabolism genes can influence the methylation of tumour suppressor genes, thereby potentially impacting on tumour behaviour.
El Galta, R, Rudd, MF, Houlston, RS, T Eisen, R el Galta, E L Webb, R S Houlston, Matakidou, A, Bridle, H, M F Rudd, H Bridle, Eisen, T, A Matakidou, Webb, EL   +13 more
core   +1 more source

ERCC1 and Small Cell Lung Cancer [PDF]

Journal of Thoracic Oncology, 2010
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Rossi G., Nannini N., Tiseo M.
openaire   +3 more sources

Chinese Expert Consensus on the Standardized Diagnosis and Treatment of 
Non‑small Cell Lung Cancer with EGFR Exon 20 Insertion Mutations (2024 Edition)

Chinese Journal of Lung Cancer
The standard clinical practice of managing the non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion (ex20ins) mutations was elaborated in Chinese expert consensus on non‑small cell lung cancer with EGFR exon ...
Chinese Society of Clinical Oncology Non-small Cell Lung Cancer Committee
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Genetic variant of miR-4293 rs12220909 is associated with susceptibility to non-small cell lung cancer in a Chinese Han population. [PDF]

PLoS ONE, 2017
Non-small cell lung cancer is one of the most common cancers and the leading cause of cancer death worldwide. Genetic variants in regulatory regions of some miRNAs might be involved in non-small cell lung cancer susceptibility and survival. rs12220909 (G/
Lixia Fan, Linqi Chen, Xiaoling Ni, Shicheng Guo, Yinghui Zhou, Chenji Wang, Yabiao Zheng, Fangyuan Shen, Vijay Kumar Kolluri, Merlin Muktiali, Zhenhong Zhao, Junjie Wu, Dunmei Zhao, Zhenglei He, Xulong Feng, Ziyu Yuan, Juan Zhang, Li Jin, Jiucun Wang, Minghua Wang   +19 more
doaj   +1 more source

Targeting DNA methyltransferases in non-small-cell lung cancer [PDF]

, 2021
Despite the advances in treatment using chemotherapy or targeted therapies, due to static survival rates, non-small cell lung cancer (NSCLC) is the major cause of cancer-related deaths worldwide.
Wilson, C., Syed, N., Al-Yozbaki, M., Jabre, I.   +3 more
core   +1 more source