Results 31 to 40 of about 680,918 (208)

Small cell carcinoma of the kidney: a case report and analysis of data from the Surveillance, Epidemiology, and End Results registry

open access: yesJournal of Medical Case Reports, 2019
Background Primary small cell carcinoma of the kidney is an extremely rare neoplasm. The clinical features of small cell carcinoma of the kidney are not well established due to its rarity and scarcity of case reports.
Charles Chu   +3 more
doaj   +1 more source

A systematic review of platinum and taxane resistance from bench to clinic: an inverse relationship [PDF]

open access: yes, 2007
We undertook a systematic review of the pre-clinical and clinical literature for studies investigating the relationship between platinum and taxane resistance.
Davey, Ross   +2 more
core   +1 more source

Iris Metastasis in Small-Cell Lung Carcinoma [PDF]

open access: yesJournal of Thoracic Oncology, 2007
Small-cell lung cancer (SCLC) is characterized by rapid growth and early metastasis. Despite its sensitivity to cytotoxic treatment, until now treatments have failed to control or cure this disease in most patients. Here, we describe a patient with SCLC in which symptoms caused by iris metastasis were the only sign of relapse after multimodality ...
Roenhorst, Anke W. J.   +3 more
openaire   +3 more sources

Expression and Significance of HPV16 E6/E7 mRNAs in the Bronchial Brush and TBNA Cells of Patients With Small Cell Lung Cancer

open access: yesTechnology in Cancer Research & Treatment, 2021
Background and Objective: Small cell lung cancer (SCLC) is characterized by rapid growth, strong invasion, and early metastasis. However, the cause of its occurrence remains unclear.
Di-Jia Zou MD   +5 more
doaj   +1 more source

Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication. [PDF]

open access: yes, 2016
The transcription factor Yin Yang 1 (YY1) is frequently overexpressed in cancerous tissues compared to normal tissues and has regulatory roles in cell proliferation, cell viability, epithelial-mesenchymal transition, metastasis and drug/immune resistance.
Bonavida, Benjamin   +2 more
core   +2 more sources

A Case Report of Small Cell Lung Carcinoma in a Patient with Progressive Diffuse Sclerosis

open access: yesJournal of Mazandaran University of Medical Sciences, 2022
Connective tissue diseases, including scleroderma, may be associated with an increased risk of lung cancer. The most common type of lung cancer associated with systemic sclerosis is adenocarcinoma or bronchoalveolar carcinoma, and small cell carcinoma is
Hojatolah Ghorbani   +4 more
doaj  

Development of taxane resistance in a panel of human lung cancer cell lines [PDF]

open access: yes, 2008
Using a selection process designed to reflect clinically relevant conditions, a panel of taxane-selected variants were developed to study further the mechanisms of resistance in lung cancer.
Breen, Laura   +3 more
core   +1 more source

Radiological and clinicopathological findings in large case series study of lung cancer in Erbil City/Iraq

open access: yesMedical Journal of Babylon, 2018
Background: Lung cancer (LC) is the most common fatal malignant neoplasm worldwide, especially in developing countries. Objective: The objective of this study was to evaluate the correlation between radiological and clinicopathological findings of the LC.
Zahir Salih Hussein   +1 more
doaj   +1 more source

Two Cases of TKI-resistant Small Cell Lung Cancer Transformation 
in Advanced Adenocarcinoma and Literature Review

open access: yesChinese Journal of Lung Cancer, 2022
Treatment of advanced non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutation with EGFR-tyrosine kinase inhibitors (EGFR-TKIs) can achieve good disease control, but it will inevitably produce drug resistance ...
Jieqiong WU   +5 more
doaj   +1 more source

Trop2 and its overexpression in cancers: regulation and clinical/therapeutic implications. [PDF]

open access: yes, 2014
Trop2 is a transmembrane glycoprotein encoded by the Tacstd2 gene. It is an intracellular calcium signal transducer that is differentially expressed in many cancers. It signals cells for self-renewal, proliferation, invasion, and survival.
Bonavida, Benjamin, Shvartsur, Anna
core   +2 more sources

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