Results 141 to 150 of about 10,910,180 (370)

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Mass of the Frobenius functional on small balls [PDF]

arXiv
We show that for a co-compact lattice in a semi-simple quasi-split real group and a fixed abstractly generic automorphic representation, Frobenius functional assigns small mass to small balls in the Orbit Method picture of P. Nelson and A. Venkatesh (Acta Math., 226, (2021), 1-209).
arxiv  

Recent Progress in Understanding Quark and Gluon Distribution Functions for Large Nuclei at Small x [PDF]

arXiv, 1993
I discuss the problem of computing the structure functions for very heavy nuclei at small Bjorken x. The approximations used in this description are physically motivated, and recent computations reviewed.
arxiv  

Brucella NyxA and NyxB dimerization enhances effector function during infection

FEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre, Arthur Louche, Francine C. A. Gérard, Laurent Terradot, Suzana P. Salcedo   +4 more
wiley   +1 more source

Bilateral Small Lebesgue Spaces [PDF]

arXiv, 2009
In this article we investigate the so-called Bilateral Small Lebesgue Spaces: prove that they are associated to the Grand Lebesgue spaces, calculate its fundamental functions and Boyd's indices find its dual spaces etc.
arxiv  

The Use of Linear Functions to Detect Hidden Periods in Data Separated into Small Sets [PDF]

, 1930
Edward L. Dodd
openalex   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

C^1-regularity for local graph representations of immersions [PDF]

arXiv, 2012
We consider immersions admitting uniform graph representations over the affine tangent space over a ball of fixed radius r>0. We show that for sufficiently small C^0-norm of the graph functions, each graph function is smooth with small C^1-norm.
arxiv  

Complete Orthonormal Sequences of Functions Uniformly Small on a Subset [PDF]

, 1957
J. A. Hummel
openalex   +1 more source