Results 161 to 170 of about 29,200,069 (297)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Implementation of Small Group Discussion in Teaching Writing Descriptive Text: Senior High School Teacher’s Experience [PDF]

open access: yes
Small group discussion is a student-centered method that is effective in increasing students’ activeness, for example, in learning writing. This research aims to explore teacher’s experience in implementing small group discussions when teaching writing ...
Miftakh, Fauzi   +2 more
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Motivating Students In Speaking English Through Small Group Discussion

open access: yes
<p><span>The purpose of this study is to find out whether small group discussion can motivate students in speaking English or not and to know the factors of students have not motivation in speaking English.
Vebiyanti Nasir, Sariwati Muhamad
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

STUDENTS’ RESPONSE TO SMALL GROUP DISCUSSION TECHNIQUE IN TEACHING READING COMPREHENSION [PDF]

open access: yes
The purpose of this study was to determine the students' response towards the teaching of reading comprehension using small group discussion. This research involved seventh grade students of a junior high school in Bogor consisting of 28 students.
Ani, Siti, Rizqiya, Rissa San
core  

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