Results 201 to 210 of about 7,610,404 (354)

The Ras small GTPase RSR1 regulates cellulase production in Trichoderma reesei. [PDF]

open access: yesBiotechnol Biofuels Bioprod, 2023
Li N   +6 more
europepmc   +1 more source

Quantifying the Single‐Cell Morphological Landscape of Cellular Transdifferentiation through Force Field Reconstruction

open access: yesAdvanced Science, EarlyView.
This study reconstructs the driving force field of fibroblast‐to‐neuron transdifferentiation from sparse single‐cell images by decomposing it into flux and time‐dependent potential gradient, extending the landscape‐flux framework to non‐steady‐state systems.
Chudan Yu   +3 more
wiley   +1 more source

The Small GTPase Rac1 Contributes to Extinction of Aversive Memories of Drug Withdrawal by Facilitating GABAA Receptor Endocytosis in the vmPFC [PDF]

open access: bronze, 2017
Weisheng Wang   +12 more
openalex   +1 more source

Extracellular Matrix Viscoelasticity Regulates Mammary Branching Morphogenesis

open access: yesAdvanced Science, EarlyView.
This study shows that mammary branching morphogenesis is regulated by extracellular matrix (ECM) stress relaxation. Slow stress‐relaxing matrices promote branching through focal adhesion signaling, collagen fiber alignment, and cell contractions, whereas fast stress‐relaxing matrices impair branching and collagen alignment.
Daniella I. Walter   +3 more
wiley   +1 more source

ARL5B Drives Esophageal Squamous Cell Carcinoma Progression via ROCK1–SREBP1‐Mediated Lipid Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Esophageal squamous cell carcinoma urgently requires new therapeutic strategies. Adenosine diphosphate‐ribosylation factor‐like protein 5B (ARL5B) is identified as a novel oncogene that remodels fatty acid metabolism through the ras homologous‐associated coiled‐coil containing protein kinase 1 (ROCK1)–sterol regulatory element‐binding protein 1 (SREBP1)
Xinyue Ma   +12 more
wiley   +1 more source

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis. [PDF]

open access: yesJ Biol Chem, 2023
Kiss RS   +27 more
europepmc   +1 more source

Golgi-resident Small GTPase Rab33B Interacts with Atg16L and Modulates Autophagosome Formation

open access: green, 2008
Takashi Itoh   +5 more
openalex   +1 more source

SpaBalance: Balanced Learning for Efficient Spatial Multi‐Omics Decoding

open access: yesAdvanced Science, EarlyView.
SpaBalance is a computational framework that harmonizes multi‐omics learning via gradient equilibrium and dual‐stream feature decomposition, achieving superior clustering accuracy, biological interpretability, and scalable integration of three or more spatial omics modalities.
Yingbo Cui   +8 more
wiley   +1 more source

Stress-mediated dysregulation of the Rap1 small GTPase impairs hippocampal structure and function. [PDF]

open access: yesiScience, 2023
Bjornson KJ   +5 more
europepmc   +1 more source

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