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Modulation of Small GTPases by Legionella
2013The pathogenic bacterium Legionella pneumophila interacts intimately with signaling molecules during the infection of eukaryotic host cells. Among a diverse set of regulatory molecules, host small GTPases appear to be prominent and significant targets. Small GTPases are molecular switches that regulate cellular signaling via their respective nucleotide-
Goody, R., Itzen, A.
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Ciba Foundation symposium, 1994
Small GTPases are converted from the GDP-bound inactive form to the GTP-bound active form by a GDP/GTP exchange reaction which is regulated by GDP/GTP exchange proteins (GEPs). We have found both stimulatory and inhibitory GEPs, which we have named GDP dissociation stimulators (GDSs) and GDP dissociation inhibitors (GDIs) respectively. We have isolated
Y, Takai +4 more
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Small GTPases are converted from the GDP-bound inactive form to the GTP-bound active form by a GDP/GTP exchange reaction which is regulated by GDP/GTP exchange proteins (GEPs). We have found both stimulatory and inhibitory GEPs, which we have named GDP dissociation stimulators (GDSs) and GDP dissociation inhibitors (GDIs) respectively. We have isolated
Y, Takai +4 more
openaire +1 more source
Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis
Cell, 2022Andy Weiss +2 more
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Dynamin, a membrane-remodelling GTPase
Nature Reviews Molecular Cell Biology, 2012Shawn M Ferguson
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Spatial and temporal coordination of mitosis by Ran GTPase
Nature Reviews Molecular Cell Biology, 2008Paul R Clarke
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