Results 221 to 230 of about 7,610,404 (354)

Deficiency of DEK proto‐oncogene alleviates allergic rhinitis by inhibiting RhoA/Ezrin‐mediated mitochondrial fission

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the mechanism of DEK regulating RhoA activation Ezrin. Upon house dust mite (HDM) stimulation, HDM‐specific immunoglobulin E (IgE) and inflammatory factors such as interleukin 4 (IL‐4), IL‐5, IL‐13, and eosinophils increased in the nasal mucosa.
Longzhu Dai, Yongde Jin, Jingmei Chai, Jianing Yang, Jiangang Wang, Mu Chen, Liangchang Li, Chongyang Wang, Guanghai Yan   +8 more
wiley   +1 more source

Split-Small GTPase Reassembly as a Method to Control Cellular Signaling with User-Defined Inputs. [PDF]

ACS Chem Biol
He Y, Faulkner BM, Weatherford RS, Hyun E, Stains CI.   +4 more
europepmc   +1 more source

Impaired Insulin Signaling Mediated by the Small GTPase Rac1 in Skeletal Muscle of the Leptin-Deficient Obese Mouse. [PDF]

Int J Mol Sci, 2023
Chan MP, Takenaka N, Satoh T.
europepmc   +1 more source

Ras family of small GTPases in immunity and inflammation

, 2012
Derek Johnson, Youhai H. Chen
openalex   +2 more sources

The role of small GTPases of the Rho/Rac family in TGF‐β‐induced EMT and cell motility in cancer [PDF]

, 2017
Hendrik Ungefroren, David P. Witte, Hendrik Lehnert   +2 more
openalex   +1 more source

Epstein–Barr Virus, Lower Vitamin D, Low Sun Exposure, and HLA‐DRB1*1501 Risk Variant Share Common Epigenetic Pathways Leading to Multiple Sclerosis Onset

Annals of Neurology, EarlyView.
Objectives Multiple sclerosis (MS) onset risk factors include Epstein–Barr virus (EBV) indices (including host response), lower serum 25‐vitamin D (25(OH)D) levels, low sun exposure, and HLA‐DRB1*1501. The underlying molecular mechanisms are unclear. Here, we examined mediation through differential DNA methylation (DNAm) to better understand possible ...
Steve Simpson‐Yap, Ellen Morwitch, Samuel A. Tanner, Sarah M. Thomson, Alex Eisner, Rod A. Lea, Trevor J. Kilpatrick, Jeannette Lechner‐Scott, Rodney J. Scott, Alexandre Xavier, Vicki E. Maltby, Robyn M. Lucas, Bruce V. Taylor, Brett A. Lidbury, Simon A. Broadley, Ingrid van der Mei, Mehari Woldemariam Merid, Boris Novakovic, Richard Saffery, Anna Karin Hedström, Pernilla Stridh, Tomas Olsson, Maja Jagodic, Lars Alfredsson, Anne‐Louise Ponsonby, for the Ausimmune Investigator Group, Caron Chapman, Alan Coulthard, Keith Dear, Terry Dwyer, Trevor Kilpatrick, Robyn Lucas, Tony McMichael, Anne‐Louise Ponsonby, Bruce Taylor, Patricia Valery, Ingrid van der Mei, David Williams   +37 more
wiley   +1 more source

Various methods to detect small GTPase activation: from radioisotope-based methods to the Small GTPase ActIvitY ANalysing (SAIYAN) system. [PDF]

J Biochem
Maeda M, Saito K.
europepmc   +1 more source

Rho family small GTPase Rif regulates Wnt5a-Ror1-Dvl2 signaling and promotes lung adenocarcinoma progression. [PDF]

J Biol Chem, 2023
Nishita M, Kamizaki K, Hoshi K, Aruga K, Nishikaku I, Shibuya H, Matsumoto K, Minami Y.   +7 more
europepmc   +1 more source

Chemoproteomic-enabled characterization of small GTPase Rab1a as a target of an N-arylbenzimidazole ligand's rescue of Parkinson's-associated cell toxicity

, 2021
A. Katherine Hatstat, Baiyi Quan, Morgan A. Bailey, Michael C. Fitzgerald, Michaela C. Reinhart, Dewey G. McCafferty   +5 more
openalex   +2 more sources

The small GTPase RAB37 functions as an organizer for autophagosome biogenesis

Autophagy, 2018
Ying Song, Dantong Shang, Hanhua Cheng, R. Zhou   +3 more
semanticscholar   +1 more source