Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Small Intestine-Targeted Long-Acting Oral Insulin Formulation Based on Engineered Milk Protein Nanoparticles. [PDF]
Thamizhchelvan AM +9 more
europepmc +1 more source
P‐glycoprotein in sheep liver and small intestine: gene expression and transport efflux activity [PDF]
M. Ballent +8 more
openalex +1 more source
Smart Catheters for Diagnosis, Monitoring, and Therapy
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman +12 more
wiley +1 more source
Impact of fiber molecular structure on resistance to digestion using the infogest and rat small intestine extract protocols. [PDF]
Boukid F +3 more
europepmc +1 more source
Analysis of interleukin-4 and interleukin-10 and their association with the lymphocytic infiltrate in the small intestine of patients with coeliac disease. [PDF]
Conrad Beckett +5 more
openalex +1 more source
This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao +8 more
wiley +1 more source
Calcifying fibrous tumor of the small intestine. [PDF]
Ibrahim Z +3 more
europepmc +1 more source
Three Cases of Perforation of the Small Intestine Due to Ingested Foreign Bodies.
Satoshi Yodonawa +4 more
openalex +2 more sources

