Results 131 to 140 of about 63,392 (262)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

A Flash Group Creation Algorithm for P300 Brain-Computer Interface Integration with Irregular Assistive Technology Keyboard Layouts. [PDF]

Sensors (Basel)
Huggins JE, Biswas P, Huggins JK, Chandel R.   +3 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Exploring Acylcarnitine Metabolism Using Reverse Metabolomics. [PDF]

Anal Chem
Keys AJ, Wiener DJ, Pacini SM, Sun C, Sandusky LE, Zhong H, Gentry EC.   +6 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A spin-orbit torque-based key generation system with key concealment and attack detection through irreversible physical changes. [PDF]

Sci Adv
Xu Y, Duan W, Wu H, Wang Y, Qin T, Zhang S, Guo Z, Wan M, Song M, You L.   +9 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

PhysioKey: Edge-AI-Driven Physiological Key Agreement for Secure Body Area Networks. [PDF]

Sensors (Basel)
Alnemari M, Al-Omair OM.
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Room-Temperature Framework Oxygen Isotope Exchange during Interaction of Water with Hydrophilic Pure-Silica Zeolites Studied Using Nuclear Magnetic resonance Spectroscopy and Neutron Diffraction. [PDF]

J Am Chem Soc
Kelly NL, Stanzione MG, Brako-Amoafo D, Lawrence GB, Rice CM, Wheatley PS, Keys JM, Heard CJ, Fischer HE, Gibbs AS, Ashbrook SE, Morris RE.   +11 more
europepmc   +1 more source