Results 101 to 110 of about 194,563 (311)
Shipping Through Sea Ice: Impacts on Marine Habitats and Best Practices [PDF]
, 2017 As the result of Arctic climate change and an increase in shipping season length, there is a growing interest in Arctic shipping operations. Sea ice serves as an important habitat for marine mammals, therefore, shipping through sea ice could lead to ...
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Global priorities for conservation across multiple dimensions of mammalian diversity [PDF]
, 2017 Conservation priorities that are based on species distribution, endemism, and vulnerability may underrepresent biologically unique species as well as their functional roles and evolutionary histories.
Brum, F. T. +8 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
The Bowhead Whale, Balaena mysticetus: Its Historic and Current Status [PDF]
, 1995 The bowhead whale, Balaena mysticetus, is currently listed as endangered under the Endangered Species Act of 1973 and as depleted under the Marine Mammal Protection Act of 1972.
Rugh, David J., Shelden, Kim E. W.
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Veterinary SciencesPododermatitis (bumblefoot) occurs commonly in birds of prey and owls and shows species-specific differences in its prevalence, especially between falcons and hawks.
Rebekka Schwehn +7 more
doaj +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Blood Vessel Topography of the Feet in Selected Species of Birds of Prey and Owls
Veterinary SciencesBirds of prey and owls are susceptible to diseases of and traumatic injuries to their feet, which regularly require surgical intervention. A precise knowledge of the blood vessel topography is essential for a targeted therapy.
Rebekka Schwehn +7 more
doaj +1 more source
Road Zone Effects in Small-Mammal Communities
Ecology and Society, 2009 Our study focused on the putative effects of roads on small-mammal communities in a high desert region of southern Utah. Specifically, we tested whether or not roads create adjacent zones characterized by lower small- mammal densities, abundance, and ...
John A. Bissonette, Silvia A. Rosa
doaj +1 more source