Results 81 to 90 of about 194,563 (311)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Malayan porcupines in moonlight: Assessing nocturnal activity patterns, with a review of porcupine distributions in Bangladesh

Global Ecology and Conservation
Many aspects of Hystricidae porcupine ecology in South Asia, including that of the Malayan porcupine (Hystrix brachyura), remain poorly studied. Part of this species’ global range falls within Bangladesh, where the presence and distribution of porcupines
Muntasir Akash, Abigail Gazzard, Rifa Nanziba, Sultan Ahmed, Haris Debbarma, Tania Zakir   +5 more
doaj   +1 more source

Habitat fragmentation and anthropogenic factors affect wildcat Felis silvestris silvestris occupancy and detectability on Mt Etna [PDF]

, 2019
Knowledge of patterns of occupancy is crucial for planning sound biological management and for identifying areas which require paramount conservation attention.
Anile S., Devillard S., Lo Valvo M., Mattucci F., Ragni B., Rovero F.   +5 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Myiasis in European hedgehogs (Erinaceus europaeus)

Veterinary Quarterly
Myiasis due to parasitic fly larvae (maggots) can have major consequences for animal health and welfare. The European hedgehog Erinaceus europaeus is frequently presented in rehabilitation centres and veterinary practices due to health problems ...
Karolin Schütte, Andrea Springer, Florian Brandes, Maximilian Reuschel, Michael Fehr, Christina Strube   +5 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Variação intraespecífica da cor da pelagem de uma espécie de pequeno roedor sul-americano [PDF]

, 2016
Intra-specific color variation is often underestimated by researchers, and among mammalian species, intra-specific differences in coloration are poorly documented for most species.
Barquez, Ruben Marcos, Colombo, Elisa Margarita, Sandoval Salinas, Maria Leonor, Sandoval, Jose Domingo   +3 more
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

With super SDMs (machine learning, open access big data, and the cloud) towards more holistic global squirrel hotspots and coldspots

Scientific Reports
Species-habitat associations are correlative, can be quantified, and used for powerful inference. Nowadays, Species Distribution Models (SDMs) play a big role, e.g.
Moriz Steiner, F. Huettmann, N. Bryans, B. Barker   +3 more
doaj   +1 more source

The Threatened Status of Steller Sea Lions, Eumetopias jubatus, under the Endangered Species Act: Effects on Alaska Groundfish Fisheries Management [PDF]

, 1995
In April 1990, the Steller sea lion, Eumetopias jubatus, was listed as threatened under the U.S. Endangered Species Act by emergency action. Competitive interactions with the billion-dollar Alaska commercial groundfish fisheries have been suggested as ...
Berg , Ronald J., Ferrero, Richard C., Fritz, Lowell W.   +2 more
core