A high-throughput fluorescent DNA cleavage assay for discovering bacterial DNA gyrase poisons. [PDF]
Dias M +9 more
europepmc +1 more source
Topology‐Orchestrated Multi‐physical Energy Control in Turtle Shell‐Inspired Metamaterials
A turtle shell‐inspired lattice metamaterial efficiently manages acoustic, fluid‐thermal, and mechanical energy flows simultaneously. The unique hybrid‐coupling architecture achieves superior sound attenuation via pore‐cavity resonance, facilitates effective airflow transport, and maximizes mechanical energy absorption through multistage cell ...
Xi Wang +3 more
wiley +1 more source
Antibody display technologies from phages to cells: translational bottlenecks and AI-enabled opportunities. [PDF]
Sahu A +7 more
europepmc +1 more source
Solvent‐Guided Chiral Assemblies and Chemical Doping of OEG‐Functionalized Conjugated Polymers
Solvent‐dependent aggregation pathways dictate whether conjugated polymers form chiral lyotropic liquid‐crystalline assemblies or achiral packed aggregates. Mapping solvent‐controlled β₁ and β2 states reveals that weaker backbone association favors β₁ aggregates and reorganizable twisted mesophases, whereas stronger backbone association favors β2 ...
Sanghyun Jeon +10 more
wiley +1 more source
Comprehensive Curation and Harmonization of Small-Molecule MS/MS Libraries in Spectraverse. [PDF]
Gupta V +4 more
europepmc +1 more source
Navigating Lipid Nanostructure Design Space Through Continuous Microfluidic Automation
LipidXplorer is a novel microfluidic platform which enables rapid navigation of lipid particle design space for high‐resolution phase mapping, lipid nanoparticle optimization, membrane biophysics, and functional nanomaterial discovery. It combines programmable composition control, continuous nanoparticle formation, and automated well‐plate collection ...
Bradley Diggines +10 more
wiley +1 more source
Engineering Murine Cross-Reactivity Into an Affibody to Human Death Receptor 5. [PDF]
Kuo TH, Vunnam N, Sachs JN, Hackel BJ.
europepmc +1 more source
This work investigates the heterogeneous nucleation of CsPbBr3${\rm CsPbBr}_3$ nanocrystal superlattices along the faces of 2D PEA2PbBr4${\rm PEA}_2{\rm PbBr}_4$ layered perovskite microcrystals. Core–crown and core–shell heterostructure morphologies are obtained.
Umberto Filippi +6 more
wiley +1 more source
Toward the rational design of oncogenic TASK-3 channel inhibitor peptides and nanoconjugate complexes. [PDF]
Zúñiga L +4 more
europepmc +1 more source
A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte +21 more
wiley +1 more source

