Results 271 to 280 of about 194,605 (341)

High-Throughput Screens of Repurposing Hub and DOS Chemical Libraries Reveal Compounds with Novel and Potent Inhibitory Activity Against the Essential Non-Neuronal Acetylcholinesterase of <i>Schistosoma mansoni</i> (SmTAChE). [PDF]

Int J Mol Sci
Skelly PJ, Da'dara AA.
europepmc   +1 more source

A Microfluidic Multiplex Sorter for Strain Development

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
A new multiplex method for high‐throughput screening of yeast strains based on glucoamylase production is presented. Droplets containing single mutant yeast cells are incubated for enzyme production. A sorting platform divides mutants by their high‐ and mid‐activity levels.
Chiara Leal‐Alves, Sebastien Dumont, Zhiyang Deng, Sarah Alkhaldi, Ziuwin Leung, Michelle Oeser, Steve C. C. Shih   +6 more
wiley   +1 more source

Rationally minimizing natural product libraries using mass spectrometry. [PDF]

mSystems
Ness M, Peramuna T, Wendt KL, Collins JE, King JB, Paes R, Santos NM, Okeke C, Miller CR, Chakrabarti D, Cichewicz RH, McCall L-I.   +11 more
europepmc   +1 more source

Exploring 3D Printing and Electrospinning Technologies for Advanced Porous Membrane Fabrication: A Review

Advanced Materials Technologies, EarlyView.
This paper contrasts electrospinning and 3D printing for porous membrane fabrication, evaluating their evolution, cost, resolution, mechanical traits, and scalability. While 3D printing excels in material diversity and industrial adaptability, electrospinning achieves finer resolution and thermal resilience.
Eya Kacem, Han Dong Suk, Deepalekshmi Ponnamma, Mohamed K Hassan, Alaa Hawari, Basheer A. Alshammari, Maryam Al‐Ejji   +6 more
wiley   +1 more source

Short Scalable Route to Bis-morpholine Spiroacetals and Oxazepane Analogues: Useful 3D-Scaffolds for Compound Library Assembly. [PDF]

J Org Chem
Kovari D, Male L, Roper KA, Mang CP, Kunz O, Cox LR.   +5 more
europepmc   +1 more source

How to Manufacture Photonic Metamaterials

Advanced Materials Technologies, EarlyView.
Metamaterials boast applications such as invisibility and “hyperlenses” with resolution beyond the diffraction limit, but these applications haven’t been exploited in earnest and the market for them hasn’t grown much likely because facile and economical methods for fabricating them without defect has not emerged.
Apurba Paul, Gregory Timp
wiley   +1 more source

Facile Fabrication of Large‐Area Biofunctionalized Metallic Nanostructures for High Performance Affinity Plasmonic Biosensors

Advanced Materials Technologies, EarlyView.
A novel approach enables facile and reproducible fabrication of gold nanoparticle arrays with tunable near‐infrared plasmonic properties and enhanced sensing accuracy. Using advanced lithography and ion milling, combined with innovative surface chemistry, the approach minimizes ohmic losses and non‐specific sorption, improving biomolecular detection ...
Dario Cattozzo Mor, Adam Benjamin Plšek, Prasanth Asokan, Van‐Truc Vu, Gizem Aktug, Elena Giordani, Elena Ricciardi, Jiri Perutka, Kamil Önder, Ladislav Fekete, Zdeněk Hubička, Chun‐Jen Huang, Jakub Dostalek   +12 more
wiley   +1 more source

Small Molecules Targeting the Structural Dynamics of AR-V7 Partially Disordered Proteins Using Deep Ensemble Docking. [PDF]

J Chem Theory Comput
Karatzas P, Brotzakis ZF, Sarimveis H.
europepmc   +1 more source

The Role of Theoretical Calculations for INVEST Systems: Complementarity Between Theory and Experiments and Rationalization of the Results

Advanced Optical Materials, EarlyView.
Theoretical lessons are key for molecules presenting an inverted singlet‐triplet excited state (e.g. S1 and T1) energy difference. This perspective provides a snapshot of the role played by calculations in last years, not only to anticipate experimental findings but also for driving high‐throughput virtual screenings, as well as the main challenge to ...
Ángel José Pérez‐Jiménez, Yoann Olivier, Juan Carlos Sancho‐García   +2 more
wiley   +1 more source

Introducing "Identification Probability" for Automated and Transferable Assessment of Metabolite Identification Confidence in Metabolomics and Related Studies. [PDF]

Anal Chem
Metz TO, Chang CH, Gautam V, Anjum A, Tian S, Wang F, Colby SM, Nunez JR, Blumer MR, Edison AS, Fiehn O, Jones DP, Li S, Morgan ET, Patti GJ, Ross DH, Shapiro MR, Williams AJ, Wishart DS.   +18 more
europepmc   +1 more source