Results 281 to 290 of about 645,880 (357)

Artificial Intelligence as the Next Visionary in Liquid Crystal Research

Advanced Functional Materials, EarlyView.
The functions of AI in the research laboratory are becoming increasingly sophisticated, allowing the entire process of hypothesis formulation, material design, synthesis, experimental design, and reiterative testing to be automated. In our work, we conceive how the incorporation of AI in the laboratory environment will transform the role and ...
Mert O. Astam, Ouassim L'Karkouri, Danqing Liu   +2 more
wiley   +1 more source

A Benchmark Set of Bioactive Molecules for Diversity Analysis of Compound Libraries and Combinatorial Chemical Spaces. [PDF]

J Chem Inf Model
Neumann A, Klein R.
europepmc   +1 more source

Amyloidogenic Peptide Fragments Designed From Bacterial Collagen‐like Proteins Form Hydrogel

Advanced Functional Materials, EarlyView.
This study identified amyloidogenic sequence motifs in bacterial collagen‐like proteins and exploited these to design peptides that self‐assemble into β‐sheet fibers and form hydrogels. One hydrogel supported healthy fibroblast growth, showing promise for biocompatible materials. Our work demonstrates that bacterial sequences can be harnessed to create
Vamika Sagar, Xuen J Ng, Lukas Lechel, Ashish Chand Rajwar, Hendrik Bargel, Abhishek A. Jalan   +5 more
wiley   +1 more source

Generation of an Induced Pluripotent Stem Cell‐Derived Alveolar Type II In Vitro Model to Study Influenza A Virus Infection and Drug Treatments

Advanced Healthcare Materials, EarlyView.
Patient‐specific induced pluripotent stem cells (iPSCs) can be differentiated into alveolar type II cells (iAT2s), expanded as 3D alveolospheres, and grown at physiologically relevant air–liquid interface (ALI). This study shows for the first time the infectability of iAT2s by the influenza A virus (IAV) and proves their responsiveness to the well ...
Lena Gauthier, Hristina Koceva, Yann Bachelot, Rosanne W. Koutstaal, Puck B. van Kasteren, Marc Thilo Figge, Christian Eggeling, Alexander Sandy Mosig   +7 more
wiley   +1 more source

Discovery of a first-in-class SLIT2 binder disrupting the SLIT2/ROBO1 axis <i>via</i> DNA-encoded library (DEL) screening. [PDF]

RSC Med Chem
Yuan S, Abdel-Rahman SA, García Vázquez N, Nada H, Calvo-Barreiro L, Kuncewicz K, Gabr MT.   +6 more
europepmc   +1 more source

PepFoundry: A Pipeline for Building Machine-Learning Ready Representations of Nonstandard Peptides Containing Cycles, Non-natural Residues, Polymer Units, and More. [PDF]

J Chem Inf Model
Garzon Otero D, Akbari O, Mandapati A, Bilodeau C.   +3 more
europepmc   +1 more source

Advancing large-molecule discovery with a unified digital platform for data analysis and workflow management. [PDF]

MAbs
Natali E, Hersch J, Freiberg C, Steigele S.   +3 more
europepmc   +1 more source

Prediction of Protein-Ligand Binding Affinities Using Atomic Surface Site Interaction Points. [PDF]

J Chem Inf Model
Zator KJ, Storer MC, Hunter CA.
europepmc   +1 more source

A quantitative high-throughput screening pipeline to identify small molecule inhibitors of Chikungunya nsP2 protease. [PDF]

Sci Rep
Li S, Hu X, Ahn YM, Medina A, Ye L, Heffner A, Messing S, Denson JP, Esposito D, Lee EM, Martinez NJ.   +10 more
europepmc   +1 more source

Development of an On-DNA Platform Molecule Bearing a Diazidestructure and Its Application to DEL Synthesis. [PDF]

Int J Mol Sci
Miyachi H, Koshimizu M, Ratanasak M, Shigeta Y, Suzuki M.   +4 more
europepmc   +1 more source