Results 311 to 320 of about 645,880 (357)
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ChemInform Abstract: Structural Diversity of Small Molecule Libraries.
ChemInform, 2001AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Anne Marie Munk Joergensen +1 more
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ENCODING TECHNIQUES FOR POOL LIBRARIES OF SMALL ORGANIC MOLECULES*
Journal of Receptors and Signal Transduction, 2001This review covers encoding techniques for small-organic-molecule pool libraries, one of the most challenging and powerful techniques in combinatorial chemistry.
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Diversity Oriented Synthesis of Small Molecule Libraries
ChemInform, 2006AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
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ChemInform Abstract: Carbohydrate‐Derived Small‐Molecule Libraries
ChemInform, 2008AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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Orthogonality of SFC versus HPLC for Small Molecule Library Separation
Journal of Combinatorial Chemistry, 2010Preparative HPLC and HPLC-MS are well established as the methods of choice for purification of pharmaceutical library compounds. Recent advances in supercritical fluid chromatography (SFC) have now made SFC a viable alternative to HPLC for this application. One of the potential arguments for using SFC in place of, or in addition to, HPLC is that it may
Harold N, Weller +10 more
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ChemInform Abstract: Solution Phase Combinatorial Libraries of Small Organic Molecules
ChemInform, 2000AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Rafael Ferritto +4 more
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OBOC Small-Molecule Combinatorial Library Encoded by Halogenated Mass-Tags
Organic Letters, 2004[reaction: see text] A bromine-/chlorine-containing mass-tag encoding strategy for a small-molecule OBOC combinatorial library is reported. The resulting MALDI FTMS isotope pattern of each tag clearly defines the component building blocks of each "hit" bead in an 1890-member demonstration library screened on-bead for binding against streptavidin via ...
Sung Hee, Hwang +6 more
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DIRECT DECONVOLUTION TECHNIQUES FOR POOL LIBRARIES OF SMALL ORGANIC MOLECULES*
Journal of Receptors and Signal Transduction, 2001The tremendous development of combinatorial chemistry during the last few years has contributed to increase steadily the options for a chemist to synthesize a chemical library, and many excellent r...
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Identification of Small Molecule Modulators of MicroRNA by Library Screening
2016MicroRNAs (miRNAs) function as oncogenes or tumor suppressors and are dysregulated in cancer. miRNAs therefore represent promising therapeutic targets for cancer. Small molecules that could modulate the expression of miRNAs would thus have potential as anticancer agents.
Zhangang, Xiao, Yangchao, Chen
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