Results 171 to 180 of about 442,180 (329)

Circulating pancreatic cancer exosomal RNAs for detection of pancreatic cancer

Molecular Oncology, 2019
Diagnostic biomarkers for the early diagnosis of pancreatic cancer are needed to improve prognosis for this disease. The aim of this study was to investigate differences in the expression of four messenger RNAs (mRNAs: CCDC88A, ARF6, Vav3, and WASF2) and
Tatsuya Kitagawa, Keisuke Taniuchi, Makiko Tsuboi, Masahiko Sakaguchi, Takuhiro Kohsaki, Takehiro Okabayashi, Toshiji Saibara   +6 more
doaj   +1 more source

Machine learning discoveries of ASCL2-X synergy in ETC-1922159 treated colorectal cancer cells [PDF]

arXiv
Achaete-scute complex homolog 2 (ASCL2) codes a part of the basic helix-loop-helix (BHLH) transcription factor family. WNTs have been found to directly affect the stemness of the tumor cells via regulation of ASCL2. Switching off the ASCL2 literally blocks the stemness process of the tumor cells and vice versa.
arxiv  

Plant small nuclear RNAs. Nucleolar U3 snRNA is present in plants: partial characterization [PDF]

, 1985
Tamás Kiss, Márta Tóth, Ferenc Solymosy   +2 more
openalex   +1 more source

Small nucleolar RNA 78 promotes the tumorigenesis in non-small cell lung cancer

Journal of experimental & clinical cancer research : CR, 2015
BackgroundAccumulating evidence suggests that dysregulated snoRNA may play a role in the development of malignancy. In the present study, we investigated the role of SNORD78 in the tumorigenesis of non-small cell lung cancer (NSCLC).MethodsWe determined ...
D. Zheng, Jie Zhang, J. Ni, Jie Luo, Jiying Wang, Liang Tang, Ling Zhang, Li Wang, Jian-fang Xu, B. Su, Gang Chen   +10 more
semanticscholar   +1 more source

Y12C mutation disrupts IMPDH cytoophidia and alters cancer metabolism

The FEBS Journal, EarlyView.
IMPDH, the rate‐limiting enzyme for de novo GTP synthesis, can form polymers and cytoophidia to enhance activity by reducing GTP inhibition. In this study, a Y12C mutation in IMPDH2 was introduced via ABEmax base‐editing in human cancer cell lines to disrupt IMPDH polymerisation.
Chia‐Chun Chang, Min Peng, Gerson Dierley Keppeke, Li‐Kuang Tsai, Ziheng Zhang, Li‐Mei Pai, Li‐Ying Sung, Ji‐Long Liu   +7 more
wiley   +1 more source

TaSED interacts with TaSPA synergistically regulating SDS‐sedimentation volume in bread wheat

Journal of Integrative Plant Biology, EarlyView.
Wheat TaSED is a positive regulator of SDS‐sedimentation volume, an indicator of gluten strength and thus baking properties. TaSED interacts with the transcription factor TaSPA regulating wheat storage protein gene expression, altering protein composition and affecting SDS‐sedimentation volume, providing a valuable genetic resource for improving wheat ...
Shanshan Zhai, Runqi Zhang, Xinhao Meng, Guoyu Liu, Jiazheng Yu, Huanwen Xu, Hongyao Lou, Shidian Wen, Mingshan You, Chaojie Xie, Jie Liu, Zhongfu Ni, Qixin Sun, Baoyun Li   +13 more
wiley   +1 more source

The Effect of Galactose on the Expression of Genes Regulated by Rrp6p [PDF]

, 2017
Gene expression is a multi-faceted phenomenon, governed not only by the sequence of nucleotides, but also by the extent to which a particular gene gets transcribed, how the transcript is processed, and whether or not the transcript ever makes it out of ...
Callahan, Kevin, Pelkowski, Mary Megan
core   +1 more source

The Benyvirus RNA Silencing Suppressor Is Essential for Long-Distance Movement, Requires Both Zinc-Finger and NoLS Basic Residues but Not a Nucleolar Localization for Its Silencing-Suppression Activity

Molecular Plant-Microbe Interactions, 2013
The RNA silencing-suppression properties of Beet necrotic yellow vein virus (BNYVV) and Beet soil-borne mosaic virus (BSBMV) cysteine-rich p14 proteins have been investigated.
Sotaro Chiba, Kamal Hleibieh, Alice Delbianco, Elodie Klein, Claudio Ratti, Véronique Ziegler-Graff, Salah Bouzoubaa, David Gilmer   +7 more
doaj   +1 more source

Multi-species stochastic models: small RNA regulation of gene expression [PDF]

arXiv, 2009
The processes, resulting in the transcription of RNA, are intrinsically noisy. It was observed experimentally that the synthesis of mRNA molecules is driven by short, burst-like, events. An accurate prediction of the protein level often requires one to take these fluctuations into account.
arxiv  

Selective changes in vasopressin neurons and astrocytes in the suprachiasmatic nucleus of Prader–Willi syndrome subjects

Journal of Neuroendocrinology, Volume 37, Issue 5, May 2025.
Abstract The hypothalamic suprachiasmatic nucleus (SCN) hosts the central circadian pacemaker and regulates daily rhythms in physiology and behavior. The SCN is composed of peptidergic neuron populations expressing arginine vasopressin (AVP) and vasoactive intestinal polypeptide (VIP), as well as glial cells.
Felipe Correa‐da‐Silva, Jari B. Berkhout, Pim Schouten, Margje Sinnema, Constance T. R. M. Stumpel, Leopold M. G. Curfs, Charlotte Höybye, Ahmed Mahfouz, Onno C. Meijer, Alberto M. Pereira, Eric Fliers, Dick F. Swaab, Andries Kalsbeek, Chun‐Xia Yi   +13 more
wiley   +1 more source