Results 21 to 30 of about 114,793 (255)
Chengshi guidao jiaotong yanjiu[Objective] To address the issues of poor operational stability and ride comfort in the actual operation of single-axle monorail trains, it is aimed to investigate the rational values of minimum horizontal curve radius and curve speed limit for single ...
DU Zixue, PI Yang, YANG Zhen
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Influence of Urban Underground Spiral Ramp Curve Design on Vehicle Running Performance
Promet (Zagreb)Urban underground spiral ramps’ continuous curves and the monotonous tunnel environment increase driving safety risks and reduce vehicle stability.
Liwei ZHENG +4 more
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FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
机车电传动, 2020 As the axle weight of the locomotive continues to increase, the wheel-rail wear is intensified, and rail corrugation on the small radius curve becomes more and more common.
Zhiwei LIU +3 more
doaj
Seismic response of small-radius planar curved tunnels
Yantu gongcheng xuebao, 2019 A three-dimensional model for small-radius planar curved tunnels with different bending angles is established to investigate their seismic response. The influences of bending angle, amplitude and type of ground motion are considered. The seismic response
MU Jia-hao , WANG Guo-bo
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FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
An Image Processing Approach to Measuring the Sphericity and Roundness of Fracturing Proppants
IEEE Access, 2019 Before being applied in oil fields, it is necessary to evaluate the quality of the fracturing proppants, for which sphericity and roundness are the two important parameters.
Xinrong Lyu +3 more
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source