Results 61 to 70 of about 7,596,148 (257)
RNA interference, growth and differentiation appear normal in African trypanosomes lacking Tudor staphylococcal nuclease. [PDF]
, 2010 Ribonucleases play important roles in the RNA interference (RNAi) pathway. The Dicer endonuclease converts double-stranded (ds)RNA into small interfering (si)RNA and the Slicer endonuclease, as a component of the RNA induced silencing complex (RISC ...
Louise E. Kemp +9 more
core +1 more source
Open Life SciencesRafflesiaceae is a family of endangered plants whose members are solely parasitic to the tropical grape vine Tetrastigma (Vitaceae). Currently, the genetics of their crosstalk with the host remains unexplored.
Wicaksono Adhityo +5 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP [PDF]
, 2013 Through controlling the nuclear level of active positive transcription elongation factor b (P-TEFb), the 7SK small nuclear RNA (snRNA) functions as a key regulator of RNA polymerase II transcription.
Kiss, T. +4 more
core +1 more source
Frontiers in Molecular Biosciences, 2022 Regulator of chromatin condensation 1 (RCC1) is the major guanine nucleotide exchange factor of RAN GTPase, which plays a key role in various biological processes such as cell cycle and DNA damage repair. Small nucleolar RNA host gene 3 (SNHG3) and small
Kai Hu +4 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Research Progress in Plant Antiviral Silencing: Argonaute-Centered Perspective
Guangdong nongye kexueIn the long-term evolution process, plants have evolved multi-layered defense mechanisms to sense and respond to the invasion of harmful organisms such as viruses, to adapt to the adverse environment and avoid attacks from harmful organisms.
Zhaoyun WANG, Jinli XIONG, Xiu WANG
doaj +1 more source
Small RNA modifications in Alzheimer's disease
Neurobiology of Disease, 2020 BackgroundWhile significant advances have been made in uncovering the aetiology of Alzheimer's disease and related dementias at the genetic level, molecular events at the epigenetic level remain largely undefined.
Xudong Zhang +7 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
, 2019 <p>Data supporting the release of the NEBNext Small RNA kit (E7300, E7330, E7580, E7560).</p ...
Langhorst, Bradley W.
core +1 more source