Results 91 to 100 of about 15,601,125 (299)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Implications and Ramifications of a Sample-Size Approach to Intuition [PDF]

open access: yes
[...from the chapter] In the present article, we delineate a different approach, which is by no means inconsistent, but largely overlaps with the aforementioned definitions.
Fiedler, Klaus, Kareev, Yaakov
core  

An investigation of skewness, sample size, and test standardisation [PDF]

open access: yes, 2014
In psychological assessment, a raw score transformation is the first step in the clinical decision-making process. During this process, clinicians will transform a raw score typically using linear standardised scores and a normative sample with ...
Piovesana, Adina M.
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

"Small" sample size

open access: yesThe Southwest Respiratory and Critical Care Chronicles, 2023
Shengping Yang, Gilbert Berdine
openaire   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

The Tokophobia Severity Scale (TSS): measurement model, power and sample size considerations.

open access: yes, 2021
: To examine the measurement model of the Tokophobia Severity Scale and consider issues of statistical power and sample size from the original instrument development study.
Marshall, Claire A   +5 more
core   +1 more source

iLDA: A new dimensional reduction method for non-Gaussian and small sample size datasets

open access: yesEgyptian Informatics Journal
High-dimensional non-Gaussian data is widely found in the real world, such as in face recognition, facial expressions, document recognition, and text processing.
Usman Sudibyo   +4 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Impact of Small Group Size on Neighborhood Influences in Multilevel Models [PDF]

open access: yes
Objective: Although there is a growing body of literature on sample size in multilevel or hierarchical modeling, few studies have examined the impact of group sizeMultilevel, Neighborhood, Body Weight, Obesity, Sample ...
Cohen, Deborah   +6 more
core  

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