Results 81 to 90 of about 1,598,901 (264)

Construction of whole stress-strain curve by small punch test and inverse finite element

open access: yesResults in Physics, 2018
Small punch test is applied to estimate mechanical properties and damage evolution by a miniature specimen. Combining small punch test and inverse finite element, the elastoplastic parameters in Hollomon model and damage parameters in Gurson-Tvergaard ...
Kaishang Li, Jian Peng, Changyu Zhou
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Intersubband energies in strain-compensated InGaN/AlInN quantum well structures

open access: yesAIP Advances, 2016
Intersubband transition energies in the conduction band for strain-compensated InGaN/AlInN quantum well (QW) structures were investigated as a function of strain based on an effective mass theory with the nonparabolicity taken into account.
Seoung-Hwan Park, Doyeol Ahn
doaj   +1 more source

The Small Strain Stiffness of a Carbonate Stiff Clay

open access: yesSoils and Foundations, 1995
ABSTRACT Knowledge of the small strain stiffness of the heavily overconsolidated Gault Clay, which has up to 30% calcium carbonate content, is rather limited. This has resulted in some difficulties in the analysis and design of structures constructed in the Gault.
Ng, Charles Wang Wai CIVL   +2 more
openaire   +3 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Spatial constraints and stochastic seeding subvert microbial arms race.

open access: yesPLoS Computational Biology
Surface attached communities of microbes grow in a wide variety of environments. Often, the size of these microbial community is constrained by their physical surroundings.
Raymond Copeland   +3 more
doaj   +1 more source

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