Results 71 to 80 of about 2,969,214 (294)

Constitutive behavior of Port-Said Clay under seismic and small strain static conditions

open access: yesAin Shams Engineering Journal, 2018
Port-Said Clay is very soft to firm clay deposited in the delta of an old tributary of the Nile at the east of Port-Said, Egypt. Despite the detailed characterization carried out for Port-Said Clay, no tests were carried out to measure its seismic or ...
Mohamed F. Mansour
doaj   +1 more source

Stress and Strain in Flat Piling of Disks

open access: yes, 2003
We have created a flat piling of disks in a numerical experiment using the Distinct Element Method (DEM) by depositing them under gravity. In the resulting pile, we then measured increments in stress and strain that were associated with a small decrease ...
Arthur J. R. F.   +17 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

An effect of a purely dissipative process of microstresses on plane strain gradient plasticity problems [PDF]

open access: yesTheoretical and Applied Mechanics, 2018
This article considers a plane strain gradient plasticity theory of the Gurtin–Anand model [M. Gurtin, L. Anand, A theory of strain gradient plasticity for isotropic, plastically irrotational materials Part I: Small deformations, J. Mech. Phys. Solids 53
Borokinni Adebowale   +2 more
doaj   +1 more source

An elastoplastic framework for granular materials becoming cohesive through mechanical densification. Part II - the formulation of elastoplastic coupling at large strain

open access: yes, 2010
The two key phenomena occurring in the process of ceramic powder compaction are the progressive gain in cohesion and the increase of elastic stiffness, both related to the development of plastic deformation.
Alessandro Gajo   +28 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Assessment of cardiac strain in small - scale aluminium casting works.

open access: yesInternational Journal of Occupational Safety and Health, 2012
Background: The occupational health status scenario in unorganised sector is not impressive. There is a lack of awareness on occupational health and safety issues and manual labour is still obligatory.
Rajib Biswas   +3 more
doaj   +3 more sources

Comparison and application of small strain shear moduli from field and laboratory measurements

open access: yesYantu gongcheng xuebao, 2019
The small-strain shear modulus plays an important role in the calculations of ground seismic response and deformation in deep excavations. The values of the small strain shear modulus G0 of Shanghai soils by field and laboratory tests are investigated ...
CHEN Shao-jie 1, 2, GU Xiao-qiang 1,2, GAO Guang-yun 1, 2
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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