Results 71 to 80 of about 1,598,901 (264)

Bounding surface constitutive model for soft soils considering characteristics of small-strain stiffness and its application in engineering

Yantu gongcheng xuebao
The construction of an excavation pit induces complex loading-unloading stress paths in the surrounding soils, while the commonly used constitutive models are insufficient to reflect the over-consolidation and small-strain stiffness characteristics ...
LIANG Fayun 1, ZHENG Hanbo 1, LI Lin 2, WANG Rulu 3, YAN Jingya 3
doaj   +1 more source

Quantitative two-dimensional strain mapping of small core–shell FePt@Fe3O4 nanoparticles

New Journal of Physics, 2016
We report a facile one-pot chemical synthesis of colloidal FePt@Fe _3 O _4 core–shell nanoparticles (NPs) with an average diameter of 8.7 ± 0.4 nm and determine their compositional morphology, microstructure, two-dimensional strain, and magnetic ...
Marianne Monteforte, Shoko Kobayashi, Le D Tung, Koichi Higashimine, Derrick M Mott, Shinya Maenosono, Nguyen T K Thanh, Ian K Robinson   +7 more
doaj   +1 more source

Heterogeneity of the Abnormal Prion Protein (PrPSc) of the Chandler Scrapie Strain

Pathogens, 2013
The pathological prion protein, PrPSc, displays various sizes of aggregates. In this study, we investigated the conformation, aggregation stability and proteinase K (PK)-sensitivity of small and large PrPSc aggregates of mouse-adapted prion strains.
Takashi Yokoyama, Shirou Mohri, Morikazu Imamura, Yoshifumi Iwamaru, Kentaro Masujin, Kazuo Kasai   +5 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Small Strain Characteristics of Soils in Hualien, Taiwan

Soils and Foundations, 2000
The Hualien Large-Scale Seismic Test (HLSST) program is currently to investigating soil-structure interaction during large earthquakes in Hualien, a region in Taiwan of high seismicity. This paper summarizes the laboratory tests, including cyclic triaxial tests, conducted to obtain small strain characteristics of the soils for dynamic response analysis
TANAKA, YUKIHISA, KUDO, KOJI, NISHI, KOICHI, OKAMOTO, TOSHIRO, KATAOKA, TETSUYUKI, UESHIMA, TERUYUKI   +5 more
openaire   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Assessment of small strain modulus in soil using advanced computational models. [PDF]

Sci Rep, 2023
Fan H, Hang T, Song Y, Liang K, Zhu S, Fan L.   +5 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Coupled Effect of Nutritional Food Molecules and Lactobacillus reuteri Surface Protein Interaction on the Bacterial Gastrointestinal Tolerance

Foods
Lactobacillus reuteri, which is present in fermented foods, can produce LPxTG motif proteins (LMPs) to help the strain resist gastrointestinal fluid environmental stress and enhance the adherence and colonizing properties.
Ao Zhang, Mingjuan Ou, Peng Wu, Kaige Zheng, Haiqian Zhang, Yixing Yu, Yuxing Guo, Tao Zhang, Daodong Pan, Zhen Wu   +9 more
doaj   +1 more source