Results 101 to 110 of about 2,530,483 (266)
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
CSD-YOLOv8s: Dense Sheep Small Target Detection Model Based on UAV Images
智慧农业ObjectiveThe monitoring of livestock grazing in natural pastures is a key aspect of the transformation and upgrading of large-scale breeding farms. In order to meet the demand for large-scale farms to achieve accurate real-time detection of a large ...
WENG Zhi, LIU Haixin, ZHENG Zhiqiang
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Small target detection based on modified local reverse entropy operator
Tongxin xuebao, 2013 A small-target detection approach was proposed,which is based on the modified local reverse entropy operator and the improved region growing technology.The approa adopted the fact that the emergence of small target could lead to the large change of local
He DENG +3 more
doaj
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
IFD-YOLO: A Lightweight Infrared Sensor-Based Detector for Small UAV Targets
SensorsThe detection of small targets in infrared imagery captured by unmanned aerial vehicles (UAVs) is critical for surveillance and monitoring applications. However, this task is challenged by the small target size, low signal-to-noise ratio, and the limited
Fu Li, Xuehan Lv, Ming Zhao, Wangyu Wu
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
AgronomyRoot system analysis remains methodologically challenging in plant research: traditional soil cultivation obstructs comprehensive root observation, whereas hydroponic visualization lacks ecological relevance due to soil environment exclusion—a critical ...
Kunhong Li +7 more
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FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source