Results 201 to 210 of about 37,476 (270)

Updates on the role of TRIM proteins in AIDS: molecular mechanisms and potential for interventions. [PDF]

Front Immunol
Chen J, Chen S, Xu Y, Wang X, Jiang M.
europepmc   +1 more source

A New Vista of Opportunity in Diabetes Management: Natural Product‐Based β‐cell Preservation

Food Chemistry International, EarlyView.
Preserving functional β‐cells via natural products offers promising strategy for diabetes treatment. ABSTRACT A defining characteristic of diabetes is β‐cell failure, in which β‐cells cannot modulate insulin secretion to compensate for escalating insulin resistance, pushing forward disease development.
Yi‐San Lee, Tien‐Fen Kuo, Chun‐Yen Yang, Greta Yang, Wen‐Chin Yang   +4 more
wiley   +1 more source

Identification and characterization of novel <i>SUMO</i> genes in bread wheat. [PDF]

PeerJ
Ibrahim EI, Attia KA, Ghazy A, Kimiko I, Al-Doss A.   +4 more
europepmc   +1 more source

Indirect ubiquitination independent of endogenous ubiquitination machinery for targeted protein degradation. [PDF]

Commun Chem
Furuhata T, Yoshida K, Fujita R, Miyamoto J, Moriyama C, Masuda-Ozawa T, Tsuchiya H, Saeki Y, Okamoto A.   +8 more
europepmc   +1 more source

Landscape of Protein Post-Translational Modifications in Age-Related Neurodegenerative Disorders: Implications in Protein Aggregation, Altered Cellular Processes, and Therapeutics. [PDF]

ACS Omega
Singh AK, Kundu TK.
europepmc   +1 more source

Protein modification by a eukaryotic-like ubiquitin-related modifier in the hyperthermophilic archaeon <i>Saccharolobus islandicus</i>. [PDF]

mSystems
Cao J, Xiong D, Zheng X, Yuan W, Huang L.   +4 more
europepmc   +1 more source

Importance of SUMOylation Consensus Sequence of MAFK in Regulating EMT, Tumor Growth, Stemness, and Drug Resistance. [PDF]

Cancer Sci
Cao TLD, Okita Y, Yahatabara R, Elhinnawi MA, Azmi NU, Poullikkas T, Motohashi H, Kato M.   +7 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Ecological drivers of Promethearchaeati's specialization for deep subsurface environments. [PDF]

Commun Biol
Smith L, Lloyd KG.
europepmc   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source