Results 221 to 230 of about 37,476 (270)

Heterogeneous nuclear ribonucleoprotein K in cancer biology and its therapeutic applications (Review). [PDF]

Mol Med Rep
Qin Y, Zhou Y.
europepmc   +1 more source

SUMOylation is destined for regulatory T cell-related immune dysregulation. [PDF]

Cell Death Discov
Qian J, Yu L, Tian M, Li X, Bai X, Yang J, Deng R, Liu Q, Lyu A, Xiao C, Liu Y.   +10 more
europepmc   +1 more source

DrugDomain 2.0: Comprehensive database of protein domains-ligands/drugs interactions across the whole Protein Data Bank. [PDF]

Comput Struct Biotechnol J
Medvedev KE, Schaeffer RD, Grishin NV.
europepmc   +1 more source

The Interplay Between the Ubiquitin-Proteasome System and Oxidative Stress: A Future Perspective in Eye Diseases. [PDF]

Antioxidants (Basel)
Tundo GR, Zingale GA, Pandino I, Peroni E, Sbardella D, Bocedi A.   +5 more
europepmc   +1 more source

A specific nanobody-based affinity chromatography resin as a platform for small ubiquitin-related modifier fusion protein purification.

Journal of Chromatography A, 2023
As an excellent fusion tag for expressing heterologous proteins, yeast SUMO (small ubiquitin-related modifier) has unique advantages such as improving solubility, promoting stability, and reducing degradation, but it lacks a simple and rapid purification
Zongqing Huang, Haoju Hua, Xiuzhen Du, Zipeng Zhen, Wei Zhao, Jun Feng, Ji-An Li   +6 more
semanticscholar   +4 more sources

PIAS proteins as regulators of small ubiquitin-related modifier (SUMO) modifications and transcription.

Biochemical Society Transactions, 2007
Transcriptional activity of signal-dependent transcription factors, including nuclear receptors, relies on interacting co-regulator proteins, many of which possess protein-modifying activity. SUMOs (small ubiquitin-related modifiers) and their conjugation pathway components act as co-regulator proteins for numerous transcription factors that also are ...
J. Palvimo
semanticscholar   +4 more sources

Mechanical Softening of a Small Ubiquitin-Related Modifier Protein Due to Temperature Induced Flexibility at the Core.

The Journal of Physical Chemistry B, 2018
Despite the growing interest in the thermal softening of proteins, the mechanistic details of it are far from understood. β-Grasp proteins have globular shape with compact structure and they are mechanically resilient.
S. Bhattacharya, Sri Rama Koti Ainavarapu   +1 more
semanticscholar   +4 more sources

Non-covalent interaction between nucleocapsid protein of Tula hantavirus and small ubiquitin-related modifier-1, SUMO-1.

Virus Research, 2003
To find cellular binding counterparts for the nucleocapsid protein (N) of Tula hantavirus (TULV), two cDNA libraries were screened using yeast two-hybrid systems based on LexA and Gal4 transcription factors. Five cDNA clones encoding SUMO-1 (Small Ubiquitin-related MOdifier, also known as sentrin) were selected in the LexA system.
Pasi Kaukinen, A. Vaheri, A. Plyusnin
semanticscholar   +4 more sources

Screening method for isopeptides from small ubiquitin-related modifier-conjugated proteins by ion mobility mass spectrometry.

Analytical Chemistry, 2011
Posttranslational modification by the small ubiquitin-related modifier (SUMO) is a highly regulated modification, which is often restricted to very specific cellular events. A number of analytical strategies for identification of SUMOylated proteins have been previously reported in the literature. A new screening method for SUMOylated peptides based on
Quentin Dumont, David L Donaldson, W. Griffith   +2 more
semanticscholar   +4 more sources