Results 1 to 10 of about 1,093,638 (350)

Small-vessel disease in the brain

American Heart Journal Plus, 2023
Cerebral small-vessels are generally located in the brain at branch points from major cerebral blood vessels and perfuse subcortical structures such as the white matter tracts, basal ganglia, thalamus, and pons.
Amita Singh, Gabriel Bonnell, Justin De Prey, Natalie Buchwald, Kyrillos Eskander, Keith J. Kincaid, Christina A. Wilson   +6 more
doaj   +4 more sources

Cerebral small vessel disease: A review.

Advances in Clinical and Experimental Medicine, 2021
Cerebral small vessel disease (CSVD) is the most common, chronic and progressive vascular disease. The changes affect arterioles, capillaries and small veins supplying the white matter and deep structures of the brain.
J. Chojdak-Łukasiewicz, E. Dziadkowiak, A. Zimny, B. Paradowski   +3 more
semanticscholar   +5 more sources

Cerebral Small Vessel Disease and Alzheimer's Disease: A Review

Frontiers in Neurology, 2020
Alzheimer's disease (AD) is the most common cause of dementia. Despite this, clear pathophysiology for AD has not been confirmed, and effective treatments are still not available.
Hae Won Kim, Jeongho Hong, Jae Cheon Jeon   +2 more
doaj   +2 more sources

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

Lancet Neurology, 2013
Joanna M. Wardlaw, Eric E. Smith, Geert Jan Biessels, Charlotte Cordonnier, Franz Fazekas, Richard Frayne, Richard I. Lindley, John T. O’Brien, Frederik Barkhof, Oscar Benavente, Sandra E. Black, Carol Brayne, Monique M.B. Breteler, Hugues Chabriat, Charles DeCarli, Frank‐Erik de Leeuw, Fergus Doubal, Marco Duering, Nick C. Fox, Steven M. Greenberg, Vladimir Hachinski, Ingo Kilimann, Vincent Mok, Robert van Oostenbrugge, Leonardo Pantoni, Oliver Speck, Blossom C. M. Stephan, Stefan Teipel, Anand Viswanathan, David J. Werring, Christopher Chen, Colin Smith, Mark A. van Buchem, Bo Norrving, Philip B. Gorelick, Martin Dichgans   +35 more
openalex   +3 more sources

Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer’s disease

Molecular Neurodegeneration, 2023
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular injuries in cerebral large and small vessels and is a key driver of age-related cognitive decline.
Yasuteru Inoue, Francis Shue, G. Bu, T. Kanekiyo   +3 more
semanticscholar   +1 more source

Cerebral Small Vessel Disease, Hypertension, and Vascular Contributions to Cognitive Impairment and Dementia

HYPERTENSION, 2023
Hypertension-associated cerebral small vessel disease is a common finding in older people. Strongly associated with age and hypertension, small vessel disease is found at autopsy in over 50% of people aged ≥65 years, with a spectrum of clinical ...
A. Hainsworth, Hugh S. Markus, Julie A. Schneider   +2 more
semanticscholar   +1 more source

Isosorbide Mononitrate and Cilostazol Treatment in Patients With Symptomatic Cerebral Small Vessel Disease

JAMA Neurology, 2023
Key Points Question Can modulators of cerebrovascular endothelial function, including isosorbide mononitrate (ISMN; a nitric oxide donor) and cilostazol (a phosphodiesterase-3 inhibitor), improve long-term outcomes after lacunar ischemic stroke? Findings
J. Wardlaw, L. Woodhouse, I. Mhlanga, K. Oatey, A. Heye, J. Bamford, V. Cvoro, F. Doubal, T. England, Ahamad Hassan, A. Montgomery, J. O'Brien, C. Roffe, N. Sprigg, D. Werring, P. Bath   +15 more
semanticscholar   +1 more source

Cerebral small vessel disease: Recent advances and future directions

International Journal of Stroke, 2022
Cerebral small vessel disease (SVD) causes lacunar stroke and intracerebral hemorrhage, and is the most common pathology underlying vascular cognitive impairment.
H. Markus, Frank Erik de Leeuw
semanticscholar   +1 more source

Association of inflammatory markers with cerebral small vessel disease in community-based population

Journal of Neuroinflammation, 2022
This study investigated the relationships of neutrophil count (NC), neutrophil-to-lymphocyte ratio (NLR) and systemic immune-inflammation index (SII) with cerebral small vessel disease (CSVD).
Li-Na Jiang, Xueli Cai, Dong-xiao Yao, J. Jing, Lerong Mei, Yingying Yang, Shan Li, A. Jin, Xia Meng, Hao Li, Tiemin Wei, Yongjun Wang, Yuesong Pan, Yilong Wang   +13 more
semanticscholar   +1 more source

Effect of Long-term Continuous Cardiac Monitoring vs Usual Care on Detection of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease: The STROKE-AF Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2021
Importance Patients with ischemic stroke attributed to large- or small-vessel disease are not considered at high risk for atrial fibrillation (AF), and the AF incidence rate in this population is unknown.
R. Bernstein, H. Kamel, C. Granger, J. Piccini, Pramod Sethi, J. Katz, Carola Alfaro Vives, P. Ziegler, Noreli Franco, L. Schwamm   +9 more
semanticscholar   +1 more source