Results 31 to 40 of about 1,093,638 (350)

HTRA1-related autosomal dominant cerebral small vessel disease

Chinese Medical Journal, 2021
. Background. Homozygous or compound heterozygous mutations in high temperature requirement serine peptidase A1 (HTRA1) gene are responsible for cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL ...
Jing-Yi Liu, Yi-Cheng Zhu, Li-Xin Zhou, Yan-Ping Wei, Chen-Hui Mao, Li-Ying Cui, Bin Peng, Ming Yao, Xin Chen   +8 more
doaj   +1 more source

Association of small vessel disease with tau pathology

Acta Neuropathologica, 2022
Emerging evidence suggests that small vessel disease (SVD) is a risk factor for clinical dementia and may contribute to AD neuropathological changes. Watershed brain regions are located at the most distal areas between arterial territories, making them ...
A. Kapasi, L. Yu, V. Petyuk, K. Arfanakis, D. Bennett, J. Schneider   +5 more
semanticscholar   +1 more source

Large-vessel correlates of cerebral small-vessel disease [PDF]

Neurology, 2013
Our aim was to investigate the relationship of carotid structure and function with MRI markers of cerebral ischemic small-vessel disease.The study comprised 1,800 participants (aged 72.5 ± 4.1 years, 59.4% women) from the 3C-Dijon Study, a population-based, prospective cohort study, who had undergone quantitative brain MRI and carotid ultrasound.
Pierre Boutouyrie, Mahmoud Zureik, Christophe Tzourio, Christophe Tzourio, Sabrina Schilling, Bernard Mazoyer, Fernando Pico, Yi-Cheng Zhu, Yi-Cheng Zhu, Marion Brisset, Stéphane Laurent, Carole Dufouil, Carole Dufouil, Stéphanie Debette, Stéphanie Debette   +14 more
openaire   +4 more sources

Advances in the Role of Endothelial Cells in Cerebral Small Vessel Disease

Frontiers in Neurology, 2022
Cerebral small vessel disease (CSVD) poses a serious socio-economic burden due to its high prevalence and severe impact on the quality of life of elderly patients.
T. Bai, Shijia Yu, Juan Feng
semanticscholar   +1 more source

Frontal white matter lesions in Alzheimer’s disease are associated with both small vessel disease and AD-associated cortical pathology

Acta Neuropathologica, 2021
Cerebral white matter lesions (WML) encompass axonal loss and demyelination and are assumed to be associated with small vessel disease (SVD)-related ischaemia. However, our previous study in the parietal lobe white matter revealed that WML in Alzheimer’s
Kirsty E. McAleese, M. Miah, Sophie Graham, Georgina M. Hadfield, Lauren Walker, Mary Johnson, S. Colloby, Alan J. Thomas, C. DeCarli, D. Koss, J. Attems   +10 more
semanticscholar   +1 more source

Dawson's Fingers in Cerebral Small Vessel Disease

Frontiers in Neurology, 2020
To explore Dawson's fingers in cerebral small vessel disease (CSVD) and factors related to the development of Dawson's finger, we collected and analyzed clinical data of 65 patients with CSVD. We found a venous abnormality feature called Dawson's fingers
Aowei Lv, Zaiqiang Zhang, Ying Fu, Yaping Yan, Li Yang, Wenli Zhu   +5 more
doaj   +1 more source

Clinical practice guideline for cognitive impairment of cerebral small vessel disease

Aging Medicine, 2019
Cognitive impairment of cerebral small vessel disease (CSVD) is one of the most common cognitive disorders. It has a high incidence and results in heavy social burden; thus, it is essential to provide reasonable diagnosis and treatment in clinical ...
Dantao Peng, Geriatric Neurology Group, Chinese Society of Geriatrics, Clinical Practice Guideline for Cognitive Impairment of Cerebral Small Vessel Disease Writing Group   +2 more
doaj   +1 more source

Clinical implication of ticagrelor monotherapy in patients with small vessel coronary artery disease: results from the TICO randomized trial

Frontiers in Cardiovascular Medicine, 2023
BackgroundThe aim of this study was to evaluate the efficacy and safety of ticagrelor monotherapy in patients with small vessel disease compared with ticagrelor-based DAPT within the Ticagrelor Monotherapy after 3 Months in the Patients Treated with New ...
Jae Young Cho, Donghyeon Joo, Kyeong Ho Yun, Byeong-Keuk Kim, Myeong-Ki Hong, Yangsoo Jang, Seok Kyu Oh   +6 more
doaj   +1 more source

How diet affects Alzheimer's disease and small vessel disease

Lifestyle Medicine, 2022
Introduction The number of people with memory disorders is increasing worldwide. Changing certain lifestyle factors can prevent the development of those disorders. Diet is a central factor that can be changed.
Juha Lempiäinen
doaj   +1 more source

Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease

Nature Network Boston, 2021
Perivascular space (PVS) burden is an emerging, poorly understood, magnetic resonance imaging marker of cerebral small vessel disease, a leading cause of stroke and dementia.
Marie-Gabrielle Duperron, M. Knol, Quentin Le Grand, T. Evans, A. Mishra, A. Tsuchida, Gennady V. Roshchupkin, T. Konuma, D. Trégouët, J. Romero, Stefan Frenzel, M. Luciano, E. Hofer, M. Bourgey, Nicole D Dueker, P. Delgado, S. Hilal, Rick M. Tankard, Florian Dubost, Jean Shin, Y. Saba, N. Armstrong, Constance Bordes, M. Bastin, A. Beiser, H. Brodaty, R. Bülow, C. Carrera, Christopher P L H Chen, Ching-Yu Cheng, I. Deary, P. Gampawar, J. Himali, Jiyang Jiang, T. Kawaguchi, Shuo Li, Mélissa Macalli, P. Marquis, Z. Morris, S. Muñoz Maniega, Susumu Miyamoto, M. Okawa, Matt Paradise, Pedram Parva, T. Rundek, M. Sargurupremraj, Sabrina Schilling, K. Setoh, O. Soukarieh, Y. Tabara, A. Teumer, A. Thalamuthu, J. Trollor, M. V. Valdés Hernández, M. Vernooij, U. Völker, K. Wittfeld, T. Wong, M. Wright, Junyi Zhang, Wanting Zhao, Yicheng Zhu, H. Schmidt, P. Sachdev, W. Wen, Kazumichi Yoshida, A. Joutel, C. Satizabal, R. Sacco, G. Bourque, Quentin Le Grand, M. Lathrop, T. Paus, I. Férnandez-Cadenas, Qiong Yang, B. Mazoyer, P. Boutinaud, Y. Okada, H. Grabe, K. Mather, R. Schmidt, M. Joliot, M. Ikram, F. Matsuda, C. Tzourio, J. Wardlaw, S. Seshadri, H. Adams, S. Debette   +88 more
semanticscholar   +1 more source