Results 51 to 60 of about 362,333 (255)

Cerebral small vessel disease and Alzheimer’s disease

Clinical Interventions in Aging, 2015
Zhiyou Cai,1 Chuanling Wang,1 Wenbo He,1 Hanjun Tu,2 Zhengang Tang,3 Ming Xiao,4 Liang-Jun Yan51Department of Neurology, Renmin Hospital, Hubei University of Medicine, 2Department of Basic Research Center, Hubei University of Medicine, 3Department of ...
Cai Z, Wang C, He W, Tu H, Tang Z, Xiao M, Yan LJ   +6 more
doaj  

Arterial Stiffness and Cerebral Small Vessel Disease

Frontiers in Neurology, 2018
Background and Objective: Studies on relations between arterial stiffness and full spectrum of radiological features of cerebral small vessel disease (CSVD) are scarce.
Fei-Fei Zhai, Yi-Cong Ye, Si-Yu Chen, Fa-Ming Ding, Fei Han, Xing-Lin Yang, Quan Wang, Li-Xin Zhou, Jun Ni, Ming Yao, Ming-Li Li, Zheng-Yu Jin, Li-Ying Cui, Shu-Yang Zhang, Yi-Cheng Zhu   +14 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Small vessel disease burden and functional brain connectivity in mild cognitive impairment

Cerebral Circulation - Cognition and Behavior
Background: The role of small vessel disease in the development of dementia is not yet completely understood. Functional brain connectivity has been shown to differ between individuals with and without cerebral small vessel disease.
Sofia Marcolini, Jaime D. Mondragón, Esther E. Bron, Geert J. Biessels, Jurgen A.H.R. Claassen, Janne M. Papma, Huub Middelkoop, Rudi A.J.O. Dierckx, Ronald J.H. Borra, Inez H.G.B. Ramakers, Wiesje M. van der Flier, Natasha M. Maurits, Peter P. De Deyn   +12 more
doaj   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Gait in Elderly With Cerebral Small Vessel Disease [PDF]

Stroke, 2010
Background and Purpose— Gait disorders are common in the elderly and are related to loss of functional independence and death. White matter lesions (WMLs) may be related, but only a minority of individuals with WMLs has gait disorders.
de Laat, K.F., van Norden, A.G.W., Gons, R.A.R., van Oudheusden, L.J.B., van Uden, I.W.M., Bloem, B.R., Zwiers, M.P., Zwiers, M.P., de Leeuw, F.E.   +8 more
openaire   +5 more sources

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Targeting the brain’s glymphatic pathway: A novel therapeutic approach for cerebral small vessel disease

Neural Regeneration Research
Cerebral small vessel disease encompasses a group of neurological disorders characterized by injury to small blood vessels, often leading to stroke and dementia.
Yuhui Ma, Yan Han
doaj   +1 more source

Large Vessel Disease Modifies the Relationship Between Kidney Injury and Cerebral Small Vessel Disease

Frontiers in Neurology, 2018
Background: Recent studies have shown that renal disease is associated with magnetic resonance imaging (MRI) markers of cerebral small vessel disease (CSVD), independent of traditional vascular risk factors.
Dong-Hui Ao, Fei-Fei Zhai, Fei Han, Li-Xin Zhou, Jun Ni, Ming Yao, Ding-Ding Zhang, Ming-Li Li, Xiao-Hong Fan, Zheng-Yu Jin, Li-Ying Cui, Shu-Yang Zhang, Yi-Cheng Zhu   +12 more
doaj   +1 more source

Association Between Cerebral Small Vessel Disease and Intracranial Arterial Calcification

Haseki Tıp Bülteni, 2022
Aim:Cerebral small vessel disease (CSVD) is a representative cause of stroke, cognitive impairment, and age-related disability, and it is shown to be associated with some traditional atherosclerotic risk factors.
Cansu Ozturk, Ozlem Gungor
doaj   +1 more source