Results 51 to 60 of about 1,168,068 (349)

Retinal biomarkers of Cerebral Small Vessel Disease: A systematic review

PLoS ONE, 2022
Introduction Cerebral Small Vessel Disease (CSVD), a progressive degenerative disorder of small caliber cerebral vessels, represents a major contributor to stroke and vascular dementia incidence worldwide.
Elena Biffi, Zachary Turple, Jessica A Chung, A. Biffi   +3 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Research progress of impaired cerebral hemodynamics in cerebral small vessel disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2021
Cerebral hemodynamic damage is an important mechanism in the pathogenesis of arteriolosclerotic cerebral small vessel disease (CSVD). The hemodynamic damage of cerebral small vessel disease includes the changes of blood pressure variability (BPV ...
LIU Na, XUE Yang, TANG Jie, ZHANG Miao⁃yi, REN Xue , FU Jian⁃hui   +5 more
doaj   +1 more source

Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate

Brain : a journal of neurology, 2022
Cerebral small vessel disease is a leading cause of stroke and a major contributor to cognitive decline and dementia, but our understanding of specific genes underlying the cause of sporadic cerebral small vessel disease is limited.
A. Mishra, C. Duplàa, D. Vojinovic, Hideaki Suzuki, M. Sargurupremraj, Nuno R Zilhao, Shuo Li, Traci M. Bartz, X. Jian, Wei Zhao, E. Hofer, K. Wittfeld, S. Harris, Sandra van der Auwera-Palitschka, M. Luciano, J. Bis, H. Adams, C. Satizabal, R. Gottesman, P. Gampawar, R. Bülow, S. Weiss, Miao Yu, M. Bastin, O. Lopez, M. Vernooij, A. Beiser, U. Völker, T. Kacprowski, A. Soumaré, Jennifer A. Smith, D. Knopman, Z. Morris, Yi-cheng Zhu, J. Rotter, C. Dufouil, M. V. Valdés Hernández, S. Muñoz Maniega, M. Lathrop, E. Boerwinkle, R. Schmidt, M. Ihara, B. Mazoyer, Qiong Yang, A. Joutel, E. Tournier-Lasserve, L. Launer, I. Deary, T. Mosley, P. Amouyel, C. DeCarli, B. Psaty, C. Tzourio, S. Kardia, H. Grabe, A. Teumer, C. V. van Duijn, H. Schmidt, J. Wardlaw, M. A. Ikram, M. Fornage, V. Gudnason, S. Seshadri, P. Matthews, W. Longstreth, T. Couffinhal, S. Debette   +66 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Surface-based morphometry of the cerebral cortex in cognitive impairments of varying severity in patients with age-related cerebral small vessel disease [PDF]

Digital Diagnostics
BACKGROUND: Analysis of structural magnetic resonance images is essential to assessing the main substrate of cognitive impairment in sporadic age-related cerebral small vessel disease, accounting for up to 45% of all dementia cases.
Elena I. Kremneva, Larisa A. Dobrynina, Kamila V. Shamtieva, Victoria V. Trubitsyna, Zukhra S. Gadzhieva, Angelina G. Makarova, Maria M. Tsypushtanova, Marina V. Krotenkova   +7 more
doaj   +1 more source

Association Between Cerebral Small Vessel Disease and Intracranial Arterial Calcification

Haseki Tıp Bülteni, 2022
Aim:Cerebral small vessel disease (CSVD) is a representative cause of stroke, cognitive impairment, and age-related disability, and it is shown to be associated with some traditional atherosclerotic risk factors.
Cansu Ozturk, Ozlem Gungor
doaj   +1 more source

An unusual case of isolated symmetric bilateral peripheral artery disease of the radial artery of the index finger in systemic sclerosis: A case report and literature review

Journal of the Practice of Cardiovascular Sciences, 2022
We report an extremely rare and peculiar case of symmetric peripheral small-vessel disease involving only the radial artery of the index finger sparing major vessels in an 80-year-old female with systemic sclerosis (SSc). Our case is the first literature
Debasish Das, Anindya Banerjee, Abhinav Kumar, Shashikant Singh, Subhas Pramanik   +4 more
doaj   +1 more source

Effects of Carotid Artery Stiffness on Cerebral Small‐Vessel Disease and Cognition

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2022
Carotid artery stiffness is associated with cognitive impairment and dementia, however, the underlying mechanism remains unknown. We examined the association of carotid artery stiffness with cerebral small vessel disease (CSVD) markers, cognitive ...
C. Robert, L. Ling, E. Tan, B. Gyanwali, N. Venketasubramanian, S. Lim, Lingli Gong, J. Berboso, A. Richards, Christopher L H Chen, S. Hilal   +10 more
semanticscholar   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source