Results 51 to 60 of about 329,900 (206)
Men who have sex with men and people living with HIV are disproportionately affected in the 2022 multi-country monkeypox epidemic. The smallpox vaccine can induce cross-reactive antibodies against the monkeypox virus (MPXV) and reduce the risk of ...
Dapeng Li +14 more
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Therapeutic Vaccines and Antibodies for Treatment of Orthopoxvirus Infections
Despite the eradication of smallpox several decades ago, variola and monkeypox viruses still have the potential to become significant threats to public health.
Stuart N. Isaacs, Yuhong Xiao
doaj +1 more source
Trained Immunity in Childhood Vaccination
Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai +2 more
wiley +1 more source
Smallpox vaccines for biodefense [PDF]
Few diseases can match the enormous impact that smallpox has had on mankind. Its influence can be seen in the earliest recorded histories of ancient civilizations in Egypt and Mesopotamia. With fatality rates up to 30%, smallpox left its survivors with extensive scarring and other serious sequelae.
Richard B, Kennedy +2 more
openaire +2 more sources
Exploring the Development of Vaccine Platforms, With a Particular Focus on the COVID‐19 Pandemic
ABSTRACT Vaccines have been a cornerstone of human health for more than 200 years and one of the most important tools to reduce childhood deaths caused by pathogens. The concept of vaccines is basically to take something safe, make it immunogenic and induce an immune response in the host that will protect it against something dangerous. Live attenuated
Matti Sällberg
wiley +1 more source
Grey colour is smallpox vaccination and black colour is no smallpox vaccination. CCR5 positive cell fraction of CD8 subsets in the two groups. Mean with SD. 1. Antigen Experienced (1AE), 2. Antigen Experienced (2AE), 3.
M. S. Petersen (5979293) +12 more
core +1 more source
Targeting vaccination against novel infections : risk, age and spatial structure for pandemic influenza in Great Britain [PDF]
The emergence of a novel strain of H1N1 influenza virus in Mexico in 2009, and its subsequent worldwide spread, has focused attention to the question of optimal deployment of mass vaccination campaigns.
White, Peter, Keeling, Matthew James
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Due to the discontinuation of routine smallpox vaccination after its eradication in 1980, a large part of the human population remains naïve against smallpox and other members of the orthopoxvirus genus.
Damian Jandrasits +6 more
doaj +1 more source
Are We Prepared in Case of a Possible Smallpox-Like Disease Emergence?
Smallpox was the first human disease to be eradicated, through a concerted vaccination campaign led by the World Health Organization. Since its eradication, routine vaccination against smallpox has ceased, leaving the world population susceptible to ...
Victoria A. Olson, Sergei N. Shchelkunov
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Smallpox in the Post-Eradication Era
Widespread vaccination programmes led to the global eradication of smallpox, which was certified by the World Health Organisation (WHO), and, since 1978, there has been no case of smallpox anywhere in the world.
Hermann Meyer +2 more
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