Results 1 to 10 of about 361,909 (215)
Past and Present Vaccinations in Sweden
Acta Paediatrica, EarlyView.
Sven Arne Silfverdal
wiley +1 more source
Humanized immune system animal models and their recent applications
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli +6 more
wiley +1 more source
Strategies for the Modification of Vaccinia Virus towards a Better Vaccine Vector
Vaccinia virus (VACV) confers cross-protective immunity against variola virus, the causative agent of smallpox, and has therefore been extensively exploited as a preventive vaccine.
Hao Sun, Xinwen Chen, Yun Wang
doaj +1 more source
ABSTRACT Introduction Since the onset of the 2022 multinational mpox outbreak, Brazil has reported one of the highest case burdens globally, disproportionately affecting sexual and gender diverse populations. Mpox vaccination efforts in Brazil have been limited by delayed procurement, restricted eligibility criteria and structural access barriers ...
Mayara Secco Torres Silva +10 more
wiley +1 more source
Durability of the Humoral Response to MPXV Infection
ABSTRACT Introduction Mpox virus (MPXV) re‐emerged in endemic countries in recent decades, resulting in large outbreaks in central and western Africa and a worldwide epidemic of clade IIb MPXV starting in 2022. Mpox cases in vaccinated persons, and a few documented reinfections, have raised questions about the durability of MPXV humoral immunity ...
Tara N. Palmore
wiley +1 more source
High‐affinity monoclonal antibodies (mAbs) targeting the MPXV EEV protein A35R were rapidly isolated using mRNA‐LNP vaccination and the Beacon single‐cell sorting Optofluidic platform, followed by functional profiling. One mAb, 17H1, potently neutralized authentic MPXV and conferred complete protection in vivo.
Shimeng Bai +10 more
wiley +1 more source
Men who have sex with men and people living with HIV are disproportionately affected in the 2022 multi-country monkeypox epidemic. The smallpox vaccine can induce cross-reactive antibodies against the monkeypox virus (MPXV) and reduce the risk of ...
Dapeng Li +14 more
doaj +1 more source
Le vaccin et ses simulacres : instaurer un être pour gérer une population, 1800-1865
The story of the smallpox vaccine is of particular interest for analysing the role of knowledge in the exercise of power after the Revolution. Rather than establishing compulsory vaccination, the French Government decided to intervene in the medical ...
Jean-Baptiste Fressoz
doaj +1 more source
Smallpox vaccination carries a high risk of adverse events in recipients with a variety of contra-indications for live vaccines. Although alternative non-replicating vaccines have been described in the form of replication-deficient vaccine viruses, DNA ...
Sarah Reeman +4 more
doaj +1 more source

